Protein Alignment Msx2 and C15

DIOPT Version :10

• Sequence 1: NP_038629.2
• Gene: Msx2 / 17702
• MGIID: 97169
• Length: 267
• Species: Mus musculus
• Sequence 2: NP_476873.2
• Gene: C15 / 42544
• FlyBaseID: FBgn0004863
• Length: 339
• Species: Drosophila melanogaster
• Alignment Length: 280
• Identity: 72/280 - (25%)
• Similarity: 109/280 - (38%)
• Gaps: 92/280 - (32%)

Mouse    34 SAEERRVKVSSLPFSVEALMS-------------------------------DKKPPKE------ 61
            |.:.|.....:||||:..|:|                               :|...||
  Fly    63 SEQTRSSSSENLPFSISRLLSKPFETSHHHHNNNNHLLSSSPGSSSNNNNSGEKGEEKELLQQED 127

Mouse    62 -------SPAVPPDCASAGAVL--RPLLLP----GHGVRDAHSPGPL---VKPFETASVKSENSE 110
                   :.::......:.|.|  .|.|.|    ||.:|......||   :.|...|::..:..:
  Fly   128 HDLAYKLATSIANSTYGSAAALYSYPHLYPSAAGGHVLRVPPQRTPLTWALPPLHHAALAHQAVK 192

Mouse   111 DG-------APWIQEPGRYSPPPRHMSPTTCTLRKHKTNRKPRTPFTTSQLLALERKFRQKQYLS 168
            |.       |..|..|.:...||:              .:||||.||..|:..||::|.:::||:
  Fly   193 DRLAAAFPIARRIGHPYQNRTPPK--------------RKKPRTSFTRIQVAELEKRFHKQKYLA 243

Mouse   169 IAERAEFSSSLNLTETQVKIWFQNRRAKAKRLQEAELEKLKMAAKPMLPS--------GFSLP-F 224
            .||||..:..|.:|:.|||.||||||.|.:|....|.|..:.||..::.|        ||:.| .
  Fly   244 SAERAALARGLKMTDAQVKTWFQNRRTKWRRQTAEEREAERQAANRLMLSLQAEAISKGFAPPSA 308

Mouse   225 PINS-------PLQAASIYG 237
            |:.|       ||  |:::|
  Fly   309 PLGSQGGVNGAPL--AALHG 326

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Msx2	NP_038629.2	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..42		2/7 (29%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	104..132		6/34 (18%)
		Homeodomain	143..199	CDD:459649	28/55 (51%)
C15	NP_476873.2	COG5576	<196..315	CDD:227863	44/132 (33%)
		Homeodomain	218..274	CDD:459649	28/55 (51%)