Protein Alignment Msx2 and Dbx

DIOPT Version :10

• Sequence 1: NP_038629.2
• Gene: Msx2 / 17702
• MGIID: 97169
• Length: 267
• Species: Mus musculus
• Sequence 2: NP_647677.2
• Gene: Dbx / 38254
• FlyBaseID: FBgn0261723
• Length: 741
• Species: Drosophila melanogaster
• Alignment Length: 361
• Identity: 85/361 - (23%)
• Similarity: 112/361 - (31%)
• Gaps: 159/361 - (44%)

Mouse     2 ASPTKGGDLFSSD-EEGPAVLAGPGPGPGGA---------------EGSAEERRVKVSSLPFSVE 50
            :|.:.|..:..|| ..|.:...|.|.|.|.:               |.|:..||
  Fly   279 SSSSPGSTISDSDNNHGASTANGNGSGTGNSGQDARPHELANSNPDEDSSASRR----------- 332

Mouse    51 ALMSDKKP----------------------PKESPAVPPDCASAGAVLRPLLLPGHGVRDAH--- 90
             |..||:.                      |...|..||...:.....||.....|.:...|
  Fly   333 -LTQDKQQQQQLLGAGGTGGGGGGGHGHGHPTPPPPPPPPVIAKPMPSRPTPFLPHTLNHPHLHS 396

Mouse    91 ----------SPGPLVKPFETASVKSENSEDGAPWIQEPGRYSPPPRHMSPTTCTLRKHKTNRKP 145
                      |.|..|.|....        .|.||                      .|.|..||
  Fly   397 LLAHCRNPYMSVGAQVFPLPPG--------QGFPW----------------------AHSTRGKP 431

Mouse   146 ------RTPFTTSQLLALERKFRQKQYLSIAERAEFSSSLNLTETQVKIWFQNRRAKAKRLQEAE 204
                  |..|:.||...||::|:|::|:|..:|.:.:..|.|.::||||||||||.|.:..:|.|
  Fly   432 RRGMMRRAVFSDSQRKGLEKRFQQQKYISKPDRKKLAERLGLKDSQVKIWFQNRRMKWRNSKERE 496

Mouse   205 LEKLKMAAKPMLPSGFS----LPFPINSP---LQAASIYGASYPFHRPVLPI------------- 249
            |          |.||.|    ||.. |:|   |..|..       .||:.|:
  Fly   497 L----------LASGGSRDQTLPNK-NNPNPDLSDAKC-------DRPLTPLSPSLLSPNGSATP 543

Mouse   250 PPVGLYA---------TP-------------VGYGM 263
            ||.|..|         ||             ||||:
  Fly   544 PPPGAVAKDEPPTAAVTPKSPQSVSSRSSPSVGYGL 579

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Msx2	NP_038629.2	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..42		13/55 (24%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	104..132		3/27 (11%)
		Homeodomain	143..199	CDD:459649	26/61 (43%)
Dbx	NP_647677.2	Homeodomain	437..491	CDD:459649	24/53 (45%)