Protein Alignment Msx2 and en

DIOPT Version :10

• Sequence 1: NP_038629.2
• Gene: Msx2 / 17702
• MGIID: 97169
• Length: 267
• Species: Mus musculus
• Sequence 2: NP_523700.2
• Gene: en / 36240
• FlyBaseID: FBgn0000577
• Length: 552
• Species: Drosophila melanogaster
• Alignment Length: 228
• Identity: 70/228 - (30%)
• Similarity: 96/228 - (42%)
• Gaps: 56/228 - (24%)

Mouse     2 ASPTKGGDLFSSDEEGPAVLAGPGPGPGGAEGSAEERRVKVSSLPFSVEALMSDKKPPKESPAVP 66
            |:||......||....   ||.|.|....:..|:      .||:..|             |.:..
  Fly   310 AAPTMTQPPLSSSASS---LASPPPASNASTISS------TSSVATS-------------SSSSS 352

Mouse    67 PDCASAGAVLRP-----LLLPGHGVRDAHSPGPLVKP------------------FETASVKSE- 107
            ..|:||.:.|..     |...|.|| :|.||.|...|                  .||.|..:|
  Fly   353 SGCSSAASSLNSSPSSRLGASGSGV-NASSPQPQPIPPPSAVSRDSGMESSDDTRSETGSTTTEG 416

Mouse   108 -NSEDGAPWI---QEPGRYSPPPRHMSPTTCTLRKHKTN--RKPRTPFTTSQLLALERKFRQKQY 166
             .:|....|:   :...|.|..||:..|..   .|.|||  ::|||.|::.||..|:|:|.:.:|
  Fly   417 GKNEMWPAWVYCTRYSDRPSSGPRYRRPKQ---PKDKTNDEKRPRTAFSSEQLARLKREFNENRY 478

Mouse   167 LSIAERAEFSSSLNLTETQVKIWFQNRRAKAKR 199
            |:...|.:.||.|.|.|.|:||||||:|||.|:
  Fly   479 LTERRRQQLSSELGLNEAQIKIWFQNKRAKIKK 511

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Msx2	NP_038629.2	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..42		10/39 (26%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	104..132		7/32 (22%)
		Homeodomain	143..199	CDD:459649	27/55 (49%)
en	NP_523700.2	Homeodomain	455..511	CDD:459649	27/55 (49%)
		Engrail_1_C_sig	512..542	CDD:431338	70/228 (31%)