Protein Alignment Msx2 and inv

DIOPT Version :10

• Sequence 1: NP_038629.2
• Gene: Msx2 / 17702
• MGIID: 97169
• Length: 267
• Species: Mus musculus
• Sequence 2: NP_523699.3
• Gene: inv / 36239
• FlyBaseID: FBgn0001269
• Length: 576
• Species: Drosophila melanogaster
• Alignment Length: 275
• Identity: 66/275 - (24%)
• Similarity: 98/275 - (35%)
• Gaps: 80/275 - (29%)

Mouse     7 GGDLFSSDEEGPAVLAG-------PGPGP---GGAEGSAEERRVKVSSLPF--SVEALMSDKKPP 59
            ||...|....|.:..:|       |...|   |.....|:......|||.|  |:..:.|:....
  Fly   304 GGGSVSGSSTGSSKNSGNTNGNRSPLKAPKKSGKPLNLAQSNAAANSSLSFSSSLANICSNSNDS 368

Mouse    60 KESPAVPPDCASAGAVLRPLLLPGHGVRDAHSPGPLVKPFETASVKSENSEDGAP-----WIQEP 119
            ..:........::||   |:.|       ..||.|......|.:......:.|.|     |:. .
  Fly   369 NSTATSSSTTNTSGA---PVDL-------VKSPPPAAGAGATGASGKSGEDSGTPIVWPAWVY-C 422

Mouse   120 GRYSP-PPRHMSPTTCTLRKHKT-------------------------NRKPRTPFTTSQLLALE 158
            .|||. |....||.....:|..|                         :::|||.|:.:||..|:
  Fly   423 TRYSDRPSSGRSPRARKPKKPATSSSAAGGGGGGVEKGEAADGGGVPEDKRPRTAFSGTQLARLK 487

Mouse   159 RKFRQKQYLSIAERAEFSSSLNLTETQVKIWFQNRRAKAKR------------------------ 199
            .:|.:.:||:...|.:.|..|.|.|.|:||||||:|||.|:
  Fly   488 HEFNENRYLTEKRRQQLSGELGLNEAQIKIWFQNKRAKLKKSSGTKNPLALQLMAQGLYNHSTIP 552

Mouse   200 --LQEAELEKLKMAA 212
              .:|.||::|:.||
  Fly   553 LTREEEELQELQEAA 567

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Msx2	NP_038629.2	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..42		9/44 (20%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	104..132		8/33 (24%)
		Homeodomain	143..199	CDD:459649	25/55 (45%)
inv	NP_523699.3	Homeodomain	472..528	CDD:459649	25/55 (45%)
		Engrail_1_C_sig	529..554	CDD:431338	0/24 (0%)