Protein Alignment Msx2 and unpg

DIOPT Version :10

• Sequence 1: NP_038629.2
• Gene: Msx2 / 17702
• MGIID: 97169
• Length: 267
• Species: Mus musculus
• Sequence 2: NP_477146.1
• Gene: unpg / 35942
• FlyBaseID: FBgn0015561
• Length: 485
• Species: Drosophila melanogaster
• Alignment Length: 493
• Identity: 99/493 - (20%)
• Similarity: 141/493 - (28%)
• Gaps: 271/493 - (54%)

Mouse    16 EGPAVLAGPGPGPGGAEGSAEERRVKVSS----LPFSVEALMSDKKPPKESPAVPPD-------- 68
            |.||:|      ..|..|:.|....:::|    .|||:|:|::::.|...:|..||:
  Fly     2 ERPALL------QNGEIGTMESPTTRLASKPFPKPFSIESLIANQTPATATPPSPPEERDQEQEA 60

Mouse    69 -------------CASAGAVLRPLLLP----------------------------GHGVRD---- 88
                         .::.|....||..|                            ||....
  Fly    61 EQEQELSARAMVASSALGLTQFPLYNPWLHGYFAQNHERLTHLIAGGCYLPSSPAGHPAAQQPQA 125

Mouse    89 ------------AHS---------PGPL---VKPFETAS-------------------------- 103
                        .|:         |.||   ..||..|:
  Fly   126 QAQPQPPPPHPPTHALEKQLPPTLPHPLDTRFLPFNPAAAGVAPTDLSYRRLAELMNQDYVHSLS 190

Mouse   104 -------------VKSENSEDGAPWIQEPGRYSPPPRHMSPT----------------------- 132
                         :..:.:..|...:|||   :||..|.||.
  Fly   191 VHARLQHMAAAGRMHEDQANPGMAQLQEP---TPPQAHSSPAKSGSHSPMEPALDVGMDEDFECS 252

Mouse   133 ---------TCTLRKHK-----------TN----------------------------------- 142
                     |.:.|.:.           ||
  Fly   253 GDSCSDISLTMSPRNYNGEMDKSRNGAYTNSDSEDCSDDEGAQSRHEGGGMGGKDSQGNGSSSNS 317

Mouse   143 --RKPRTPFTTSQLLALERKFRQKQYLSIAERAEFSSSLNLTETQVKIWFQNRRAKAKRL----- 200
              |:.||.||:.|||.|||:|..|:|||:.||::.::||.|:|.||||||||||||.||:
  Fly   318 KSRRRRTAFTSEQLLELEREFHAKKYLSLTERSQIATSLKLSEVQVKIWFQNRRAKWKRVKAGLT 382

Mouse   201 ------------------------------QEAELEKLKMAA-KPMLPSGFSLPFPINSPLQAAS 234
                                          |..:|||:.::. ||          .:...|.|.:
  Fly   383 SHGLGRNGTTSGTKIVVPIPVHVNRFAVRSQHQQLEKMCLSGPKP----------DLRKKLSAEA 437

Mouse   235 IYG---------ASYPFHRPVLPIPPVGLYATPVGYGM 263
            |.|         ||.|..      .|||| ...||.|:
  Fly   438 IGGFEKFSGSTNASSPSG------GPVGL-GVGVGVGV 468

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Msx2	NP_038629.2	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..42		7/25 (28%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	104..132		8/27 (30%)
		Homeodomain	143..199	CDD:459649	34/55 (62%)
unpg	NP_477146.1	Homeodomain	324..376	CDD:459649	32/51 (63%)