DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment acbp-5 and anox

DIOPT Version :9

Sequence 1:	NP_499817.2	Gene:	acbp-5 / 176800	WormBaseID:	WBGene00011731	Length:	274	Species:	Caenorhabditis elegans
Sequence 2:	NP_001027085.1	Gene:	anox / 3771728	FlyBaseID:	FBgn0064116	Length:	243	Species:	Drosophila melanogaster

Alignment Length:	256	Identity:	70/256 - (27%)
Similarity:	114/256 - (44%)	Gaps:	36/256 - (14%)

- Green bases have known domain annotations that are detailed below.

Worm    18 NQEEEPIDTLLEAKFDAATTRLPGFLTKIDQKTILKFYGLYKQAVEGPADSKKGPYWFETVARKK 82
            :.:.:.:|.|    |..||..:......|....:|.|||.||||..||. .::.|...:..|:.|
  Fly     3 DSDTDTVDEL----FHLATEHVAKQSNSIGSADLLIFYGYYKQATNGPC-KEQSPGLLQLQAKSK 62

Worm    83 FNSWLANSQMSRSRAMEAYCELMAQLDTSWDPDAETVKKSGLWEKMPSTMGVIEPEMFDDAVVH- 146
            :.:|.....||:|.|.:||.:.:.:|..:|     ..:::..|                  |||
  Fly    63 WQAWRNLGTMSQSAARQAYVQKLQELQPNW-----RSRRNPGW------------------VVHS 104

Worm   147 ----PPTKLETETEKKWFAAMRVSDIDTMRTLLRNEPEIIEAKDQYLAMTALLWATDLGCDPVVQ 207
                |......::||..|..::.:::|.:|.||  :|..:...|:: .|..:.||||.....::|
  Fly   105 IESVPLEDQRLDSEKTLFDHVKENNLDRLRELL--QPSDLVKLDEH-GMALIHWATDRNAVEIIQ 166

Worm   208 FLIENNVDVNAVDGCLQTALHFAAQCHRPLLAELLLQAGADRSALDADGLTPSECCDDEDL 268
            ||:.:...||..|...||.||:||.|......:.||:..|.....|:||.|..:..|||.:
  Fly   167 FLVRSGASVNQRDAEQQTPLHYAASCGHLEALQCLLELHASLELRDSDGQTCYDVADDEQI 227

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
acbp-5	NP_499817.2	ACBP	29..108	CDD:279259	24/78 (31%)
		Ank_2	160..253	CDD:289560	28/92 (30%)
		ANK	161..272	CDD:238125	34/108 (31%)
		ANK repeat	188..220	CDD:293786	10/31 (32%)
		ANK repeat	222..253	CDD:293786	10/30 (33%)
anox	NP_001027085.1	ACBP	10..90	CDD:279259	27/84 (32%)
		ANK	125..231	CDD:238125	34/106 (32%)
		Ank_2	125..212	CDD:289560	27/89 (30%)
		ANK repeat	148..179	CDD:293786	10/31 (32%)
		ANK repeat	181..212	CDD:293786	10/30 (33%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C160165995
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG4281
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H12465
Inparanoid	1	1.050	93	1.000	Inparanoid score	I3655
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG54934
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0005754
OrthoInspector	1	1.000	-	-		oto19107
orthoMCL	1	0.900	-	-		OOG6_104190
Panther	1	1.100	-	-	LDO	PTHR24119
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R5885
SonicParanoid	1	1.000	-	-		X1917
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	14	13.830