Protein Alignment rsks-1 and S6k

DIOPT Version :10

• Sequence 1: NP_499447.2
• Gene: rsks-1 / 176554
• WormBaseID: WBGene00012929
• Length: 550
• Species: Caenorhabditis elegans
• Sequence 2: NP_523941.2
• Gene: S6k / 38654
• FlyBaseID: FBgn0283472
• Length: 490
• Species: Drosophila melanogaster
• Alignment Length: 529
• Identity: 275/529 - (51%)
• Similarity: 349/529 - (65%)
• Gaps: 60/529 - (11%)

 Worm     1 MADVFE----FELEGHESQASPQRHAYHYDNCTEIMEDDHMYSNVADGQISAPPPSSSYMEDPMM 61
            ||||.:    |:||.|:.:..        |:.....:||.:  .:.|..:......:.:.:....
  Fly     1 MADVSDPSELFDLELHDLELQ--------DDKARDSDDDRI--ELDDVDLEPELCINLHQDTEGQ 55

 Worm    62 ESIQLCASAINPPNVRVGPEDFQLLKVLGKGGYGKVFQVRKTTGSDNGQIFAMKVLQKATIVRNQ 126
            |:||||...:||..:::||:||:|.|||||||||||||||||.|.|..:.||||||:||:||.||
  Fly    56 ETIQLCEENVNPGKIKLGPKDFELKKVLGKGGYGKVFQVRKTAGRDANKYFAMKVLKKASIVTNQ 120

 Worm   127 KDTAHTKAERNILEAVKSPFICDLLYAFQTGGKLYLILEYLSGGELFMHLEREGMFMENVAKFYL 191
            ||||||:||||||||||.|||.:|:|||||.|||||||||||||||||||||||:|:|:...|||
  Fly   121 KDTAHTRAERNILEAVKHPFIVELVYAFQTDGKLYLILEYLSGGELFMHLEREGIFLEDTTCFYL 185

 Worm   192 SEIVVSLEHLHQQGIIYRDLKPENILLDAYGHVKLTDFGLCKEEIEGDQKTHTFCGTIEYMAPEI 256
            |||:::|.|||:.||||||||||||||||.|||||||||||||.|:....|||||||||||||||
  Fly   186 SEIILALGHLHKLGIIYRDLKPENILLDAQGHVKLTDFGLCKEHIQEGIVTHTFCGTIEYMAPEI 250

 Worm   257 LMRCGHGKAVDWWSLGALMFDMLTGGPPFTAENRRKTIDKILKGRLTLPAYLSNEARDLIKKLLK 321
            |.|.|||||||||||||||||||||.||||||||:|||:.|||.:|.|||||:.|||||:::|:|
  Fly   251 LTRSGHGKAVDWWSLGALMFDMLTGVPPFTAENRKKTIETILKAKLNLPAYLTPEARDLVRRLMK 315

 Worm   322 RHVDTRLGAGLSDAEEIKSHAFFKTTDWNLVYARQLEAPFKPNIENDEDTSLFDARFTKMTPVDS 386
            |....|||:|..||..::.|.|||..:|:.|.||:||.|.||.:.:::|.|.||.|||:..||||
  Fly   316 RQEPQRLGSGPEDAAAVQIHPFFKHVNWDDVLARRLEPPIKPLLRSEDDVSQFDTRFTRQIPVDS 380

 Worm   387 PCETNFSLNGDNPFVGFTYVAPSVLEMMNKGGHGGISVAHLASSMSRAGAAKSPRKPGDPE---- 447
            |.:|..|.:.:..|.||||||||:||.|           |.|:.|......::||:..|..
  Fly   381 PDDTTLSESANLIFQGFTYVAPSILEDM-----------HRANRMPARSPRRTPRQLPDSSFRLQ 434

 Worm   448 --TASILHGGHSNLFGHGPNSEAPQAFGYGIGSQMTTTTAGGAGIQQPYQSFSGGYPEDDAMDTS 510
              :|::  |.::.|..||.:..:      |:.::.|          .|:.           |.|.
  Fly   435 FPSANV--GANAPLAMHGHSQRS------GMFARAT----------PPHH-----------MQTF 470

 Worm   511 TPRASESRE 519
            .||.|.:::
  Fly   471 APRPSPAQD 479

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
rsks-1	NP_499447.2	STKc_p70S6K	86..408	CDD:270736	226/321 (70%)
S6k	NP_523941.2	STKc_p70S6K	81..402	CDD:270736	226/320 (71%)