Protein Alignment tat-3 and CG33298

DIOPT Version :9

• Sequence 1: NP_499363.3
• Gene: tat-3 / 176498
• WormBaseID: WBGene00012360
• Length: 1411
• Species: Caenorhabditis elegans
• Sequence 2: NP_995666.1
• Gene: CG33298 / 2768929
• FlyBaseID: FBgn0032120
• Length: 1517
• Species: Drosophila melanogaster
• Alignment Length: 1457
• Identity: 568/1457 - (38%)
• Similarity: 837/1457 - (57%)
• Gaps: 216/1457 - (14%)

 Worm    26 KGHHR---RTSSLWVP-----PTR-PIFSSPTQVIKEKAENGGR--------------ILKTHPV 67
            :||.|   :|..:..|     |.| |  |:||      :..|||              :.:|...
  Fly   149 RGHSRVGSKTDFILPPGHKEEPAREP--SAPT------SATGGRGHSRQASRSESIYTLRRTEAP 205

 Worm    68 TRWL------FPTQPMLPQQ--RLVVPNNQKEP-PPRYEQPNRKYCGNRISTTKYSVLTFIPKNL 123
            ..|.      :.|.....::  |.||||:...| .|:.:.||.::.||:|.||||::|:||||||
  Fly   206 PWWKRLTLCNYNTGDKFEERSYRTVVPNHTVPPKTPKRDHPNGQFVGNKIRTTKYTLLSFIPKNL 270

 Worm   124 FEQLHRAANLYFIFIVILNMI--IGAFGKYISVLPIAFVLGITAIKDAFEDYRRYKSDQKINHST 186
            .||.||.|||||||||:||.:  |.||||.::::|:.||||:||:||.|||.||..||::||::|
  Fly   271 LEQFHRVANLYFIFIVLLNWVPEISAFGKEVAMIPVLFVLGVTAVKDLFEDRRRRASDKRINNTT 335

 Worm   187 CRVWDASQQRYRKLEWQNILVGDFVHLSHDEIIPADILLLRSSDVNGVCYVETCNLDGESNLKQR 251
            |||:|...:||:|::||.:.|||.||||::|.:||||||||:||..||||::||:||||:|||:|
  Fly   336 CRVYDGETERYKKVKWQELRVGDIVHLSNNETVPADILLLRTSDPQGVCYIDTCDLDGETNLKRR 400

 Worm   252 QAIRSMGKYHNANVPLEYSPAEFNYRIACEQPTTDVYKFEGRLEAIEGGPPLAREFTILAKENVL 316
            :.:|...:..:.     :.|::|..|:..:.|||.:|:|.|.|....|      |...::.|.:|
  Fly   401 EVVRGFEEMQSI-----FVPSKFVSRVEADAPTTKLYRFHGALIHPTG------ERVPISTECLL 454

 Worm   317 LRGCVVKNTDFVEGIVLYAGKDTKAMLNNNGPRYKRSSLEKMTNVDILWSVCTLLALCVIGAVLS 381
            ||...:||||::||||:|||.:||:||||:|||||||.:|:..|:|::|.|..||.|||:||:..
  Fly   455 LRESRLKNTDYIEGIVVYAGHETKSMLNNSGPRYKRSQVEQQMNIDVIWCVIILLILCVVGAIGC 519

 Worm   382 GVWLRTFSTPYIVPFLVFIHPNSSYHNNNDSQYKYSPSYESWFSFWSYIIVLQVMIPISLYVSIE 446
            .:||.:| |.:.||:|   .||           |.:.:.||.:.||:||::||||||:||||:||
  Fly   520 RMWLSSF-THFPVPYL---PPN-----------KLTANMESMWIFWTYIVILQVMIPLSLYVTIE 569

 Worm   447 FIKIFQVWFMSQDRNMYYDKVDKRLQCRALNITEELGQIQYVMSDKTGTLTENQMVFRRCSVNGN 511
            ..||.||:.:..:.:::..:.:|:.:|||:||||||||||::.:|||||||||:|:||||.|||:
  Fly   570 LCKILQVFHIHNNVDLFDAETNKQTECRAMNITEELGQIQHIFTDKTGTLTENKMIFRRCVVNGS 634

 Worm   512 DYGGRPVVDAVDSSLELVAS-------------TLRSDQPTEKKLQMAALAEAAAKTRRLRPSRD 563
            ||...|      |.||.:.|             .|.||        ||.|.:....|...:..::
  Fly   635 DYNHPP------SELEKIYSKPGAPAPPLIPNDNLNSD--------MAQLTQGTYLTPHAQRIQE 685

 Worm   564 PALESQLASSVLKLGADIDDPVFAFFLTMAICNTVVVNAKPHEDLMDPDGDIVNSRFAPEEVSPR 628
                                    |.:.:||||||:|.|.||.|:|:..|.|...:......:.:
  Fly   686 ------------------------FLVVLAICNTVIVGAAPHRDMMNASGIIEVQQIGNSPANLK 726

 Worm   629 RGSSLEDGFKYLADVEEESPASTQASTPVMITEENDGFEEIELIEFPE---VKTDETQMT----- 685
            .|...:   |.||     |..||..:|.::    |....:.:::..|.   ::..|::..
  Fly   727 HGKQRQ---KLLA-----SSTSTTTTTTII----NGPTTQPQVVSIPADRYIRLAESRSVTPSPP 779

 Worm   686 ----------EKEETISAEVAAKKSGSDEKDNNYNGERKE----------GKGFGILHR--PSIL 728
                      ..:.|:|...::.:|..:.:..:.:...|.          |:...:::.  .||.
  Fly   780 PNLLFALPAQSHQPTLSPISSSAESSPNSESESPSPPMKNKSLSNSISPTGRAKAVINSKITSIA 844

 Worm   729 SVPFAKLKG--MKSPFRRSVDKRSSSSTETAVAPPLHSFYDSESPDELALVEAAREYGIRLLRRR 791
            :...||.:|  ||.|     ..::.:...||...||   |::|||||||||.||..|...||.|.
  Fly   845 TFLNAKTQGKRMKLP-----SSKTGTIYRTADGRPL---YEAESPDELALVNAAYSYDCCLLNRS 901

 Worm   792 FDDVIVYLRHSTSSVKYKVLHTLPFDADRKRMSVIIRESSGLKRIIVLTKGADATVIPVLSEAFS 856
            .:.::|.:..:.::.:|::|..||||:.||.||:::|: .|.:.|::.|||||::::|||.....
  Fly   902 PNQILVSMPMAGATREYEILKVLPFDSSRKCMSIVVRQ-IGSQEIVLYTKGADSSIMPVLVPCSH 965

 Worm   857 TSARG--EEVIFKSQEHLTQYAKEGLRTLCLSMKIWTEEEYQGWKEKHEEAELDMMDKETMLAES 919
            .|..|  .|   ::|:.|.:||:||||.|.::.:.....:|..|..:|:|.|:.:.::|..|.:|
  Fly   966 NSPEGILRE---QTQQLLDRYAREGLRILVMAKRTLNSADYTDWWARHQEIEMSLENRERRLRDS 1027

 Worm   920 TLRAEQDLELLGVTAIEDRLQDGVPECIHSLREAGIRVWVLTGDKIETAVNIAYSSRLFSPSMDL 984
            ..:.|.:|.|||.|.|||||||||||.|.||..|||.||||||||.|||:|||||::||:..|:|
  Fly  1028 FAKLESNLTLLGATGIEDRLQDGVPETIASLLSAGISVWVLTGDKPETAINIAYSAKLFTQQMEL 1092

 Worm   985 LNIGANGVRAVSDLLTEHLKRIARAYEVSADAADS---FG---------LVLNASTMSYCLDPHN 1037
            :.:.|....|....:..:|.      ::..|...|   :|         ||::..|:::.|||.:
  Fly  1093 IRLTARSRDAAETAINFYLT------DMENDKTTSTLGYGQSLRKKQRALVVDGKTLTFILDPKS 1151

 Worm  1038 --LERFVKLLRGCRSVLCCRATPLQKAQLVNLAKNHLKGKVLAIGDGANDVSMIQGADVGIGLSG 1100
              :..|::|.:.|.||||||:||||||.||.:.|..|..:.||||||||||||||.||||:|:||
  Fly  1152 KLILPFLRLSKRCASVLCCRSTPLQKAYLVKVVKEELNLRTLAIGDGANDVSMIQMADVGVGISG 1216

 Worm  1101 QEGMQAVMSSDFAMARFRFLSNLLLVHGHWNYYRLAQTILYFFYKNAMLVFVIFWYQIFNGFSAQ 1165
            ||||||||::||.:.|||:|..|||.||:|.|.||::.|||||||||..||:|||||::.|||.|
  Fly  1217 QEGMQAVMAADFTLPRFRYLERLLLAHGYWCYDRLSRMILYFFYKNAAFVFLIFWYQLYCGFSGQ 1281

 Worm  1166 VPIDPVYLMVYNLIFTSVPPLLFGCLDQDASAELLLDCPRLYEQGRLGKRYRWYSFWINMLDAVW 1230
            |.:|.:|||:|||||||:|||..|..|:..:.:|||..|.||:.||||..||.:.||:.:|||::
  Fly  1282 VMMDQMYLMLYNLIFTSLPPLAIGVYDKRVAEDLLLKNPYLYKNGRLGVAYRPHDFWLILLDALY 1346

 Worm  1231 QSLVVFFICYFTYRGSNVDMWTFGHLLVTQLIIVNTFHLALFVQYWTWPMFWSMFLSVLLFFICA 1295
            ||||:||:....|..|:|.:|.||..:....:..|..|.|:.::.||.....|:.||:..|::.|
  Fly  1347 QSLVIFFVALCAYAESDVGIWEFGTTITASCLFANLVHCAIEIRSWTVLHVLSIVLSLGSFYLFA 1411

 Worm  1296 LLY-----NGFVTANWTWTNVKDPPSMVSLKSFSSLEFWMALIISVVLCLTPRYVLTTVVNTVSP 1355
            ::|     |.|...:..|         |....|:|...|:.:::|.|:.:.||.:||||..::.|
  Fly  1412 IVYDSVCMNCFGVRSSYW---------VIFVCFASAVHWLVIMLSTVVAVLPRLLLTTVRISLCP 1467

 Worm  1356 STTLRTRLGAEDGFKKKTESRFTACAV 1382
            ..:.:..|.:     |:..||..|..|
  Fly  1468 DDSTKVILQS-----KRERSRGEALLV 1489

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
tat-3	NP_499363.3	PhoLip_ATPase_N	94..152	CDD:292826	37/59 (63%)
		ATPase-Plipid	103..1357	CDD:273734	536/1321 (41%)
		Cation_ATPase	<770..848	CDD:289987	33/77 (43%)
		HAD_like	<1075..1107	CDD:304363	26/31 (84%)
		PhoLip_ATPase_C	1107..1356	CDD:292829	109/253 (43%)
CG33298	NP_995666.1	PhoLip_ATPase_N	249..299	CDD:292826	32/49 (65%)
		ATPase-Plipid	250..1473	CDD:273734	536/1325 (40%)
		E1-E2_ATPase	302..>394	CDD:278548	54/91 (59%)
		Cation_ATPase	<880..965	CDD:289987	36/85 (42%)
		HAD_like	<1177..1240	CDD:304363	41/62 (66%)
		PhoLip_ATPase_C	1223..1468	CDD:292829	109/253 (43%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C160159199
Domainoid	1	1.000	380	1.000	Domainoid score	I448
eggNOG	1	0.900	-	-		E2759_KOG0206
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H68636
Inparanoid	1	1.050	934	1.000	Inparanoid score	I174
Isobase	1	0.950	-	0	Normalized mean entropy	S3083
OMA	1	1.010	-	-		QHG53737
OrthoDB	1	1.010	-	-		D37083at33208
OrthoFinder	1	1.000	-	-		FOG0000076
OrthoInspector	1	1.000	-	-		otm14244
orthoMCL	1	0.900	-	-		OOG6_102565
Panther	1	1.100	-	-	LDO	PTHR24092
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R3512
SonicParanoid	1	1.000	-	-		X904
SwiftOrtho	1	1.000	-	-
TreeFam	1	0.960	-	-
	18	17.750