DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment ceh-13 and toy

DIOPT Version :9

Sequence 1:	NP_498655.1	Gene:	ceh-13 / 176069	WormBaseID:	WBGene00000437	Length:	202	Species:	Caenorhabditis elegans
Sequence 2:	NP_001368990.1	Gene:	toy / 43833	FlyBaseID:	FBgn0019650	Length:	655	Species:	Drosophila melanogaster

Alignment Length:	176	Identity:	46/176 - (26%)
Similarity:	79/176 - (44%)	Gaps:	22/176 - (12%)

- Green bases have known domain annotations that are detailed below.

Worm    43 WAAHPSNYIMGNGHVSPPATASGLSPPASRSSNS------SAELPTGVTASQHNTY------KWM 95
            ||.:|||  ....|::.|..||.::.||:.|..:      ..||...|..|..|::      ...
  Fly   184 WAWYPSN--TTTAHLTLPPAASVVTSPANLSGQADRDDVQKRELQFSVEVSHTNSHDSTSDGNSE 246

Worm    96 HTKRSQRPAAPKKKVIDENGTNRTNFTTHQLTELEKEFHTAKYVNRTRRTEIASNLKLQEAQVKI 160
            |.......:..:.::..:...|||:|:..|:..|||||....|.:...|..:|..:.|.||::::
  Fly   247 HNSSGDEDSQMRLRLKRKLQRNRTSFSNEQIDSLEKEFERTHYPDVFARERLADKIGLPEARIQV 311

Worm   161 WFQNRRMKEKKREKEKAFL--------ARNTWESNSPTSSCSGEDV 198
            ||.|||.|.::.||.:...        :..|..:|:|:.:.:...|
  Fly   312 WFSNRRAKWRREEKMRTQRRSADTVDGSGRTSTANNPSGTTASSSV 357

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
ceh-13	NP_498655.1	Homeobox	118..164	CDD:278475	17/45 (38%)
toy	NP_001368990.1	PAX	29..153	CDD:128645
		COG5576	<253..368	CDD:227863	28/105 (27%)
		Homeobox	269..322	CDD:395001	21/52 (40%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910