DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment ceh-13 and eyg

DIOPT Version :9

Sequence 1:	NP_498655.1	Gene:	ceh-13 / 176069	WormBaseID:	WBGene00000437	Length:	202	Species:	Caenorhabditis elegans
Sequence 2:	NP_001014582.1	Gene:	eyg / 39419	FlyBaseID:	FBgn0000625	Length:	670	Species:	Drosophila melanogaster

Alignment Length:	231	Identity:	64/231 - (27%)
Similarity:	92/231 - (39%)	Gaps:	73/231 - (31%)

- Green bases have known domain annotations that are detailed below.

Worm    17 DWPTTHSY--YPSVPSSYSPLNHHPADIWAAHPSNYIMGNGHVSPPATASGL----------SPP 69
            ::..|.:|  ||..|        ||...:..||:..:.|...|.||...|.|          .||
  Fly   227 EFARTAAYGLYPPPP--------HPYGSFTWHPAGNVPGGQGVPPPPPPSALWSVAAPTLANLPP 283

Worm    70 ASRS--------SNSSAEL--------PTGVTAS----QHNTYKWMHTKRSQRPAAPKKKVIDEN 114
            ::.|        |.|||.|        ||....|    .|:|.:          :|.:.:.||.:
  Fly   284 SAASAVPVSTCGSLSSAHLMAGGAGGTPTNRAISPGSGSHDTLE----------SADENRHIDSD 338

Worm   115 ----------GTNRTNFTTHQLTELEKEFHTAKYVNRTRRTEIASNLKLQEAQVKIWFQNRRMKE 169
                      ..|||.|:..||.||||||..:.|...:.|..::|...|.||:|::||.|||.|.
  Fly   339 YLDDDDEPKFRRNRTTFSPEQLEELEKEFDKSHYPCVSTRERLSSRTSLSEARVQVWFSNRRAKW 403

Worm   170 K--------KREKEKAFLARNTWESN-----SPTSS 192
            :        ||::.......::.:||     |||.|
  Fly   404 RRHQRMNLLKRQRSSPANPLHSQQSNDAPASSPTPS 439

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
ceh-13	NP_498655.1	Homeobox	118..164	CDD:278475	20/45 (44%)
eyg	NP_001014582.1	HTH	120..217	CDD:304362
eyg	NP_001014582.1	Homeobox	352..404	CDD:278475	24/51 (47%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910