Protein Alignment DMPK and DBF2

DIOPT Version :9

• Sequence 1: NP_001275693.1
• Gene: DMPK / 1760
• HGNCID: 2933
• Length: 655
• Species: Homo sapiens
• Sequence 2: NP_011606.3
• Gene: DBF2 / 852984
• SGDID: S000003324
• Length: 572
• Species: Saccharomyces cerevisiae
• Alignment Length: 400
• Identity: 125/400 - (31%)
• Similarity: 188/400 - (47%)
• Gaps: 77/400 - (19%)

Human    67 QSVVQEPPASESRAEPIVVRLKEVRLQRDDFEILKVIGRGAFSEVAVVKMKQTGQVYAMKIMNKW 131
            |..:.|..:|..:.|..|:|.:.::.:..|||::..:|:|.:.:|.:.:.|.|.:|.|:||:||.
Yeast   147 QIKLNEEWSSYLQREHQVLRKRRLKPKNRDFEMITQVGQGGYGQVYLARKKDTKEVCALKILNKK 211

Human   132 DMLKRGEVSCFREERDVLVNGDRRWITQLHFAFQDENYLYLVMEYYVGGDLLTLL-----SKFGE 191
            .:.|..|......|||:|......|:.:|.:||||...|||.||:..|||..|||     .|.|.
Yeast   212 LLFKLNETKHVLTERDILTTTRSEWLVKLLYAFQDLQSLYLAMEFVPGGDFRTLLINTRCLKSGH 276

Human   192 RIPAEMARFYLAEIVMAIDSVHRLGYVHRDIKPDNILLDRCGHIRLADFG-----------SCLK 245
                  ||||::|:..|::::|.|||.|||:||:|.|:|..|||:|.|||           ..:|
Yeast   277 ------ARFYISEMFCAVNALHDLGYTHRDLKPENFLIDAKGHIKLTDFGLAAGTISNERIESMK 335

Human   246 LRADG---------TVRSL-------------------VAVGTPDYLSPEILQAVGGGPGTGSYG 282
            :|.:.         |.:|:                   ..||:|||::.|:|:.       ..|.
Yeast   336 IRLEKIKDLEFPAFTEKSIEDRRKMYNQLREKEINYANSMVGSPDYMALEVLEG-------KKYD 393

Human   283 PECDWWALGVFAYEMFYGQTPFYADSTAETYGKIVHYKEHLSLPLVDEG---VPEEARDFIQRLL 344
            ...|:|:||...:|...|.|||...||.|||..:..:|:.|..|...:|   ..:...|.|.||:
Yeast   394 FTVDYWSLGCMLFESLVGYTPFSGSSTNETYDNLRRWKQTLRRPRQSDGRAAFSDRTWDLITRLI 458

Human   345 CPPETRLGRGGAGDFRTHPFFFGLDWDGLRDSVPPFTPDFEGATDTCNFD--------------- 394
            ..|..||  ......:...:|..:::..||..:|||||..:..||...||
Yeast   459 ADPINRL--RSFEHVKRMSYFADINFSTLRSMIPPFTPQLDSETDAGYFDDFTSEADMAKYADVF 521

Human   395 LVEDGLTAMV 404
            ..:|.|||||
Yeast   522 KRQDKLTAMV 531

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
DMPK	NP_001275693.1	STKc_DMPK_like	95..432	CDD:270748	118/371 (32%)
		S_TKc	97..365	CDD:214567	100/314 (32%)
		DMPK_coil	496..556	CDD:117396
DBF2	NP_011606.3	STKc_Sid2p_like	165..547	CDD:270751	119/381 (31%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C159049535
Domainoid	1	1.000	220	1.000	Domainoid score	I511
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.840