Protein Alignment DMP1 and Su(var)2-HP2

DIOPT Version :9

• Sequence 1: XP_011530007.1
• Gene: DMP1 / 1758
• HGNCID: 2932
• Length: 542
• Species: Homo sapiens
• Sequence 2: NP_610972.2
• Gene: Su(var)2-HP2 / 36621
• FlyBaseID: FBgn0026427
• Length: 3257
• Species: Drosophila melanogaster
• Alignment Length: 630
• Identity: 134/630 - (21%)
• Similarity: 226/630 - (35%)
• Gaps: 168/630 - (26%)

Human    52 QNNESEDSE-EWKGHLAQAPTPPLESSESSEGSKVSSEEQANEDPSDSTQSEEGLGSDDHQYIYR 115
            :|...:|.: |..|:..:|...||:.:|:|..:.: .::::||....:.|..:.|...:..:. :
  Fly  1191 ENPSKKDKKTEQSGNKKEAVVGPLDKTETSSSTNI-IDKKSNESFDSAMQPSDRLNQKESAFT-K 1253

Human   116 LAGGFSRSTGKGGDDKDDDEDDSGDD---TFGD--DDSGPGPKDRQEGGNSRLGSDEDS------ 169
            |:...|........|||.|....|.|   |..|  :||....|..||  |.....:|||
  Fly  1254 LSSISSPKKIMKDQDKDLDALSKGGDSNPTIRDTGEDSRQTDKKHQE--NDTKHEEEDSSKLKAN 1316

Human   170 -DDTIQASEESA-PQGQDSAQDTT----SESRELDNEDRVDSKPEGGDSTQESESEEHWVGG--- 225
             |:|..:||:.| |..:||:||:.    |:.:..:...:.:.||  .||..||:.|    ||
  Fly  1317 IDETKSSSEKDAEPISKDSSQDSAKPRLSKPKSRNKRKKNEKKP--NDSIAESDIE----GGFQV 1375

Human   226 ---------GSDGESSHGDGSELDDEGMQSDDPESIRSERGNSRMNSAGM---KSKESGENSEQA 278
                     .:..||:..|..:.|:   .:::|....:|.|..|......   ..|:....:.|.
  Fly  1376 NTETVQATCSTPSESNKKDMVKSDE---TNEEPNLSETEIGRIRKRGQAFHIENPKDDLHITPQN 1437

Human   279 NTQDSGG-----------SQLLEHPSRKIFRKSRI----------------------------SE 304
            ..|...|           |...:.|..||..|:.:                            |:
  Fly  1438 ENQSIAGVNFEKQVPLPESVESDTPIMKIPTKTYLMCTKNKTSLLSASEDPDIVLEPQKLITTSK 1502

Human   305 EDDRSELDDNNTMEEVK---------SDSTENSNS-------RDTGLSQPRRDSKGDSQ------ 347
            .|...:||:.|.:|...         ||.|...||       :.:.:..|...:|...|
  Fly  1503 GDSNPDLDNANNLETSSTQDPKEHEFSDQTFTDNSDIIPSCTKKSQIVFPTTPTKSSDQTKNSFI 1567

Human   348 -----EDSKENLSQ---------EESQNVDGPSSESSQEANLSSQENSSESQEEVVSESRGDNPD 398
                 ..||.|:|:         |||||....||.|..:..|.:...|......::..:
  Fly  1568 TPNRSPKSKRNVSKEAKRLDNSFEESQNAASESSASKVQKELRTPTASCRKLRVLIKRT------ 1626

Human   399 PTTSYVEDQEDS----------------DSSEEDSSHTLSHSKSESREEQADSESSESLNFSEES 447
            ||:|...:...|                :|.|:..|...|.|..|...: :|..::||:....||
  Fly  1627 PTSSLPTNSRKSIFKKTPAKSKRLTKILESMEKTPSREPSVSLGEVNPD-SDPVAAESVAVLHES 1690

Human   448 PESPEDENSSSQEGLQ-SHSSSAESQSEESHSEEDDSD--------------SQDSSRSKEDSNS 497
            ....|.....::|..: :..:|||....:...:|||.:              :.||::....:.|
  Fly  1691 DRDLESNEIPNEEVFEDTEEASAEDTDNKLKKKEDDHELEVNDICAASKNPITDDSTKDASSNKS 1755

Human   498 TESKSSSEEDGQLKNIEIES--------RKLTVDAY-HNKPIGDQ 533
            |:|....|...:|.|..|.:        ::||.:.. :||.:.|:
  Fly  1756 TDSDVLQETKDELSNSLINATQGEDTPIKELTEEEVPNNKTVEDE 1800

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
DMP1	XP_011530007.1	DMP1	30..542	CDD:284637	134/630 (21%)
Su(var)2-HP2	NP_610972.2	MDN1	<596..845	CDD:227596
		PTZ00449	<739..1091	CDD:185628
		PTZ00108	<1132..1374	CDD:240271	52/192 (27%)
		PTZ00121	<1720..>2291	CDD:173412	17/81 (21%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1181
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	0.900