DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment F17C8.6 and para

DIOPT Version :9

Sequence 1:	NP_497974.1	Gene:	F17C8.6 / 175626	WormBaseID:	WBGene00008911	Length:	279	Species:	Caenorhabditis elegans
Sequence 2:	NP_001259619.1	Gene:	para / 32619	FlyBaseID:	FBgn0285944	Length:	2145	Species:	Drosophila melanogaster

Alignment Length:	247	Identity:	45/247 - (18%)
Similarity:	90/247 - (36%)	Gaps:	83/247 - (33%)

- Green bases have known domain annotations that are detailed below.

Worm    42 RRVKFLLRLLKGRL--EVNDE-------------SDGLLFKHMCHEMERLHNGDDVSF-HDVLNM 90
            |.:....:|::.:|  :::|:             |:|   |.:|..:...|..:::.. ||.:..
  Fly  1076 RNIADCFKLIRNKLTNQISDQPSGERTNQISWIWSEG---KGVCRCISAEHGDNELELGHDEILA 1137

Worm    91 LSYRSVDIRKSLQLEELLQREELEYIIEEEVAKHTIRAWLENCLKNIKAKQNNTLGKMSSIGSTF 155
            .......|::..|||..: .:.:|:.|..:             :||.|.|
  Fly  1138 DGLIKKGIKEQTQLEVAI-GDGMEFTIHGD-------------MKNNKPK--------------- 1173

Worm   156 AFPQSQEVLTKGVVLTEASPEEDSLQGDKGSGKKKAQRGNSITEIVAEAQKKSVKRATDKISERR 220
                      |...|..|:.::.:.....||.|.:..:.        |:.|.|.:  |.:..|:|
  Fly  1174 ----------KSKYLNNATDDDTASINSYGSHKNRPFKD--------ESHKGSAE--TMEGEEKR 1218

Worm   221 GTLRQMQMGTYDELEEVEEDED--TDGEIRRSSFEYSGVDMIQMSHEKQLED 270
            ...:: .:|..:||:|..|.|:  .||            |:|..:|::.:.|
  Fly  1219 DASKE-DLGLDEELDEEGECEEGPLDG------------DIIIHAHDEDILD 1257

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
F17C8.6	NP_497974.1	None
para	NP_001259619.1	Ion_trans	165..436	CDD:278921
		Na_trans_cytopl	515..648	CDD:288761
		Ion_trans	835..1028	CDD:278921
		Na_trans_assoc	1054..1296	CDD:284034	45/247 (18%)
		Ion_trans	1318..1571	CDD:278921
		Na_channel_gate	1561..1613	CDD:240441
		Ion_trans	1636..1871	CDD:278921
		GPHH	1880..1930	CDD:293510
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG2301
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900