DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment idhg-1 and CG32026

DIOPT Version :9

Sequence 1:	NP_497927.2	Gene:	idhg-1 / 175598	WormBaseID:	WBGene00009440	Length:	396	Species:	Caenorhabditis elegans
Sequence 2:	NP_729420.1	Gene:	CG32026 / 317829	FlyBaseID:	FBgn0052026	Length:	719	Species:	Drosophila melanogaster

Alignment Length:	337	Identity:	133/337 - (39%)
Similarity:	208/337 - (61%)	Gaps:	14/337 - (4%)

- Green bases have known domain annotations that are detailed below.

Worm    54 VTVLPGDGIGPEMLHHVERILSAVQAPVDFEVVNLT---SKEDASEDLAEAITAIKRNGVALKGN 115
            :|::||||||||:...|.:||.|.:.|:.||.|::|   :.:..:....:.|.::.|..|.|||.
  Fly   385 ITLMPGDGIGPEISMAVIKILEAAKTPLIFEPVDVTPVLNSQGMTSVPEQVIESMNRTKVGLKGP 449

Worm   116 IETKFDNPSFVSRNLELRRQLNLYANVLHCSTIPTVPSRHTGIDMVIIRENTEGEYSGNEHEAVN 180
            :.|.. ...|.|.||.||:..|||||:..|.::|.|.:.:..:|:|.|||||||||||.||..||
  Fly   450 LMTPV-GTGFRSLNLTLRQLFNLYANIRPCRSLPGVETVYGDVDIVTIRENTEGEYSGIEHTLVN 513

Worm   181 APHPRVVESLKVVTREKSEQITRFAFQFAKKYGRKKVTAVHKANIQKLGDGLFLKVATDIA---- 241
            .    ||:|:|::||..|.::..:.||:|....|||||||.::.:.::.|||||:...::|
  Fly   514 G----VVQSIKLITRNASLRVAEYTFQYALAMKRKKVTAVAESQVMRMSDGLFLRCVREMAAKYK 574

Worm   242 -KAEYPDIEFNAMIVDNASMQLVSRPQQFDVMLMPNLYGNIISNIACGLVGGPGLVSGMNIGEDY 305
             |.:...|::....:....:.:|..|:::|::::|||||:|||:...||:||.||....|:|.:.
  Fly   575 SKMDQAGIKYEESTMTTVCLNIVQDPKRYDMLVLPNLYGDIISDTCAGLIGGLGLTPSGNVGTNG 639

Worm   306 AVFETGTRNTGTTLAGKDLANPTAFIRAAVDMLRFLGLQSHADMISDSLFRTLVDKRIHTADIGG 370
            |:||: ...|...:||||||||||.:.::|.||.::||..|||.|..::.:|:.|..|.|.|:||
  Fly   640 AIFES-VHGTAPDIAGKDLANPTALLLSSVMMLHYIGLHEHADKIEKAVLKTIRDDNIRTMDLGG 703

Worm   371 TSKSSELVQSVL 382
            .:|.||...:::
  Fly   704 KAKCSEYTDALI 715

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
idhg-1	NP_497927.2	Iso_dh	49..383	CDD:294303	133/337 (39%)
CG32026	NP_729420.1	FGF-BP1	<281..361	CDD:284004
CG32026	NP_729420.1	Iso_dh	382..718	CDD:294303	133/337 (39%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0473
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D325037at33208
OrthoFinder	1	1.000	-	-		FOG0000244
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X402
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	6	5.820