DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Meis2 and achi

DIOPT Version :9

Sequence 1:	XP_011237639.1	Gene:	Meis2 / 17536	MGIID:	108564	Length:	559	Species:	Mus musculus
Sequence 2:	NP_001286352.1	Gene:	achi / 36373	FlyBaseID:	FBgn0033749	Length:	555	Species:	Drosophila melanogaster

Alignment Length:	183	Identity:	57/183 - (31%)
Similarity:	86/183 - (46%)	Gaps:	34/183 - (18%)

- Green bases have known domain annotations that are detailed below.

Mouse   359 QKKRGIFPKVATNIMRAWLFQHLTHPYPSEEQKKQLAQDTGLTILQVNNWFINARRRIVQPMIDQ 423
            :|:||..||.:..|::.||::|..:.|||:.:|..|:|:..||:|||.||||||||||:..||.:
  Fly    94 RKRRGNLPKTSVKILKRWLYEHRYNAYPSDAEKFTLSQEANLTVLQVCNWFINARRRILPEMIRR 158

Mouse   424 S---------NRAGFLLDPSVSQGAAYS--------PEGQPMGSFVLD--------GQQHMGIRP 463
            .         :|.|..:.|:.|:.:|..        ..|.|....|:.        |:.|.||
  Fly   159 EGNDPLHFTISRRGKKVSPNCSRSSALGANLTGPNPAHGSPASEVVVGATEEVDGAGEIHEGI-- 221

Mouse   464 AGLQSMPGDYVSQGGPMG-MGMAQPSYTPPQMTPHPTQLRHGP----PMHSYL 511
            |.:.:....||.  ||.| |...:|.|....:......:.:.|    .:||.|
  Fly   222 ANVLTNFEQYVQ--GPNGQMVKMEPEYEDSVIYSWQQAIANNPMGFQSLHSSL 272

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Meis2	XP_011237639.1	Meis_PKNOX_N	129..213	CDD:374576
Meis2	XP_011237639.1	Homeobox_KN	376..415	CDD:368670	21/38 (55%)
achi	NP_001286352.1	Homeobox_KN	111..150	CDD:283551	21/38 (55%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167842729
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG0773
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.740