Protein Alignment H10E21.5 and HRD1

DIOPT Version :9

• Sequence 1: NP_497129.1
• Gene: H10E21.5 / 175169
• WormBaseID: WBGene00019185
• Length: 473
• Species: Caenorhabditis elegans
• Sequence 2: NP_014630.1
• Gene: HRD1 / 854149
• SGDID: S000005373
• Length: 551
• Species: Saccharomyces cerevisiae
• Alignment Length: 372
• Identity: 82/372 - (22%)
• Similarity: 129/372 - (34%)
• Gaps: 109/372 - (29%)

 Worm    13 LIFMRF--------------LQSSVDAVYTNVKLQCIDSEEVYGTLQTELTFSNKDGGGSTFLPA 63
            |||.||              :...:.::|||.|.. |:|..:|.....|.|
Yeast   145 LIFSRFSFNLVLLAVVDYQIITRCISSIYTNQKSD-IESTSLYLIQVMEFT-------------- 194

 Worm    64 YTDLCAPDMKFDDSQRVFFCKNCIQNCLS-----RVETAPKNILIVADVKAPNNRVSWFHVQTPV 123
                    |...|...:|     :|.||:     |.:.:..|         .||.:  .|.....
Yeast   195 --------MLLIDLLNLF-----LQTCLNFWEFYRSQQSLSN---------ENNHI--VHGDPTD 235

 Worm   124 SNIRESGKQCNVENSNAMQSPE-------------ETSTDALRSFSKTSV-LFVSISFIILMVI- 173
            .|..||.:...|.|.:.....:             |.:.|....|.||:: |.:.|.|.:.|::
Yeast   236 ENTVESDQSQPVLNDDDDDDDDDRQFTGLEGKFMYEKAIDVFTRFLKTALHLSMLIPFRMPMMLL 300

 Worm   174 -SLAWLVFYYVQRFRYAHAKDRLQRRLFNAARKALTRIPTMTITPGMTQELQSD---CAVCLD-- 232
             .:.|.:....|.........|..::|.:.         .:|:|....|...:|   |.:|:|
Yeast   301 KDVVWDILALYQSGTSLWKIWRNNKQLDDT---------LVTVTVEQLQNSANDDNICIICMDEL 356

 Worm   233 ---PYQ-----LQDVIRLLPCKHIYHKSCIDPWLLEHRTCPMCK--------NDILKHFGYWNDI 281
               |.|     .....:.|||.||.|.||:..|:...:|||:|:        |.:...|...:||
Yeast   357 IHSPNQQTWKNKNKKPKRLPCGHILHLSCLKNWMERSQTCPICRLPVFDEKGNVVQTTFTSNSDI 421

 Worm   282 RNDIQMPTNSRGIADD---FTIRLELGEQEHQAPSADVISPEANSDT 325
            .....: |:|.|||.|   |...::|......:|...:: |..|.||
Yeast   422 TTQTTV-TDSTGIATDQQGFANEVDLLPTRTTSPDIRIV-PTQNIDT 466

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
H10E21.5	NP_497129.1	HRD1	<150..325	CDD:227568	49/201 (24%)
		RING-H2_GRAIL	226..273	CDD:319582	20/67 (30%)
HRD1	NP_014630.1	HRD1	5..551	CDD:227568	82/372 (22%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910