Protein Alignment mac-1 and TER94

DIOPT Version :10

• Sequence 1: NP_496814.1
• Gene: mac-1 / 174974
• WormBaseID: WBGene00003119
• Length: 813
• Species: Caenorhabditis elegans
• Sequence 2: NP_001097249.1
• Gene: TER94 / 36040
• FlyBaseID: FBgn0286784
• Length: 826
• Species: Drosophila melanogaster
• Alignment Length: 830
• Identity: 269/830 - (32%)
• Similarity: 422/830 - (50%)
• Gaps: 171/830 - (20%)

 Worm    72 ENDEKMEEKEAMDDVQEI--PIVKALETRKRKAPAAGRKSTGQAAAAKE---------------- 118
            |.||||:.|::.|..:::  .|:|..:...|......:.......:..:
  Fly    17 EQDEKMKPKDSFDKREDLATAILKRKDRPNRLIVEEAQNDDNSVVSLSQAKMDELQLFRGDTVIL 81

 Worm   119 ----------VVLSDDS-EDE-----RAAR-------------------QLEKQIESLKTNRANK 148
                      :|||||: .||     |..|                   :..|::..|..:.:.:
  Fly    82 KGKRRKETVCIVLSDDTCPDEKIRMNRVVRNNLCVHLSDVVSVQSCPDVKYGKRVRILPIDESTE 146

 Worm   149 TVL-NLYTKKSAP-----STPVSTPKN---QATKKP-----------PGASAAPPALPRGLGAVS 193
            .|. ||:.....|     ..|:....|   :|..:|           |....||..:   :....
  Fly   147 GVTGNLFEIYLKPYFLEAYRPIHMGDNFIVRAAMRPIEFKVVLTDPEPYCIVAPETV---IFCDG 208

 Worm   194 DTISPRESH-----VKFEHIGGADRQFLEVCRLA-MHLKRPKTFATLGVDPPRGFIVHGPPGCGK 252
            |.|...|..     |.::.|||..:|..::..:. :.|:.|..|..:||.||||.:::||||.||
  Fly   209 DPIKREEEEESLNAVGYDDIGGCRKQLAQIKEMVELPLRHPSLFKAIGVKPPRGILMYGPPGTGK 273

 Worm   253 TMFAQAVAGELAIPMLQLAATELVSGVSGETEEKIRRLFDTAKQNSPCILILDDIDAIAPRRETA 317
            |:.|:|||.|.......:...|::|.::||:|..:|:.|:.|::|||.|:.:|:||||||:|:..
  Fly   274 TLIARAVANETGAFFFLINGPEIMSKLAGESESNLRKAFEEAEKNSPAIIFIDEIDAIAPKRDKT 338

 Worm   318 QREMERRVVSQLCSSLDELVLPPREKPLKDQLTFGDDGSVAIIGDSPTAAGAGVLVIGTTSRPDA 382
            ..|:|||:||||.:.:|.:                             ...:.::|:..|:||::
  Fly   339 HGEVERRIVSQLLTLMDGM-----------------------------KKSSHLIVMAATNRPNS 374

 Worm   383 VDGGLRRAGRFENEISLGIPDETAREKILEKICK-VNLAGDVTLKQIAKLTPGYVGADLQALIRE 446
            :|..|||.|||:.||.:||||.|.|.::|....| :.|..||.|:|||..:.|:|||||.:|..|
  Fly   375 IDPALRRFGRFDREIDIGIPDATGRLEVLRIHTKNMKLHDDVDLEQIAAESHGHVGADLASLCSE 439

 Worm   447 AAKVAIDRVFDTIVVKNEGHKNLTVEQIKEELDRVLAWLQGD-DDPSALSELNGGLQISFEDFER 510
            ||                      ::||:|::|.:      | :|....:|:...|.::.|:|..
  Fly   440 AA----------------------LQQIREKMDLI------DLEDDKIDAEVLASLAVTMENFRY 476

 Worm   511 ALSTIQPAAKREGFATVPDVSWDDIGALVEVRKQLEWSILYPIKRADDFAALGIDCRP-QGILLC 574
            |::...|:|.||....||:.:|.|||.|..|:|:|:..:.||::..|.|...|:  :| :|:|..
  Fly   477 AMTKSSPSALRETVVEVPNTTWTDIGGLESVKKELQELVQYPVEHPDKFLKFGM--QPSRGVLFY 539

 Worm   575 GPPGCGKTLLAKAVANETGMNFISVKGPELLNMYVGESERAVRTVFQRARDSQPCVIFFDEIDAL 639
            |||||||||||||:|||...|||||||||||.|:.||||..||.:|.:||.:.|||:||||:|::
  Fly   540 GPPGCGKTLLAKAIANECQANFISVKGPELLTMWFGESEANVRDIFDKARSAAPCVLFFDELDSI 604

 Worm   640 VPKR--SHGESSGGA-RLVNQLLTEMDGVEGRQKVFLIGATNRPDIVDAAILRPGRLDKILFVDF 701
            ...|  :.|::.|.| |::||:||||||:..::.||:|||||||||:|.|||||||||:::::..
  Fly   605 AKARGGNVGDAGGAADRVINQILTEMDGMGAKKNVFIIGATNRPDIIDPAILRPGRLDQLIYIPL 669

 Worm   702 PSVEDRVDILRKSTKNGTRPMLGEDIDFHEIAQLPELAGFTGADLAALIHESSLLALQARV---- 762
            |..:.|..||:.:.:   :..|.:::|...||::.:  ||:||||..:...:..||::..:
  Fly   670 PDDKSREAILKANLR---KSPLAKEVDLTYIAKVTQ--GFSGADLTEICQRACKLAIRQAIEAEI 729

 Worm   763 ---------------LENDESVKGVGMRHFREAASRIRPSVTEADRKKYE 797
                           ::.|:.|..:...||.||....|.||::.|.:|||
  Fly   730 RREKERAENQNSAMDMDEDDPVPEITSAHFEEAMKFARRSVSDNDIRKYE 779

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
mac-1	NP_496814.1	Nucleolin_bd	5..65	CDD:465247
		CDC48	<191..804	CDD:273521	237/638 (37%)
TER94	NP_001097249.1	CDC48	47..787	CDD:273521	260/800 (33%)