Protein Alignment gsy-1 and GlyS

DIOPT Version :9

• Sequence 1: NP_496736.1
• Gene: gsy-1 / 174924
• WormBaseID: WBGene00001793
• Length: 672
• Species: Caenorhabditis elegans
• Sequence 2: NP_731967.2
• Gene: GlyS / 41823
• FlyBaseID: FBgn0266064
• Length: 709
• Species: Drosophila melanogaster
• Alignment Length: 695
• Identity: 393/695 - (56%)
• Similarity: 506/695 - (72%)
• Gaps: 43/695 - (6%)

 Worm     6 RMPRNLSSNKIAKTIAGEDLDEEEVLEMDAGQSAREEGRFVFECAWEVANKVGGIYTVLRSKAQI 70
            ||.|..|     :..:|.||.:    ..|.|..|..|.|:.||.||||||||||||||:||||.:
  Fly    20 RMNRRFS-----RVESGADLKD----YFDRGDIASRENRWNFEVAWEVANKVGGIYTVIRSKAYV 75

 Worm    71 STEELGDQYCMFGPMKDGKWRLEVDPIE-PENRTIRAAMKRFQADGFRCMYGRWLIEGYPKVILF 134
            ||||:|:|.||.||.|:...|.|::.:| |....:..|:...::.|::...||||::|.|::|||
  Fly    76 STEEMGEQLCMMGPYKEHCARTEMEEMEFPRGNPLLDAVNSLRSRGYKIHTGRWLVDGNPQLILF 140

 Worm   135 DLGSGAVKMNEWKHELFEQCKIGIPHEDIESNDAVILGFMVALFLKHFRESVTSYT-------PL 192
            |:||.|.|::::|.|::|:|.|||||.|||:|||:|||||:|.||:.||....:|:       |.
  Fly   141 DIGSAAWKLDQFKSEMWEKCHIGIPHLDIETNDAIILGFMIAEFLEEFRNFAVTYSQNNELSAPR 205

 Worm   193 VVAHFHEWQAGVGLLMTRLWKLDIATVYTTHATLLGRHLCAGGADLYNNLDSFDLDAEAGKRKIY 257
            :|||||||||||||::.|...::||||:|||||||||:||||..|.|||||.|.:|.|||||:||
  Fly   206 IVAHFHEWQAGVGLIVLRTRLVEIATVFTTHATLLGRYLCAGNTDFYNNLDKFAVDEEAGKRQIY 270

 Worm   258 HQYCLERAACQTAHIFTTVSEITGLEAEHFLCRKPDVLTPNGLNVVKFAALHEFQNLHAQNKEKI 322
            |:|||||.|...||:|||||||||.||||.|.||||::|||||||.||:|:||||||||..||||
  Fly   271 HRYCLERGATHLAHVFTTVSEITGYEAEHLLKRKPDIITPNGLNVKKFSAIHEFQNLHAVAKEKI 335

 Worm   323 NQFIRGHFHGHLDFDLDKTLYFFTAGRYEFSNKGGDMFIESLARLNHYLKTTSDPRHMGVTVVAF 387
            |:|:||||:||:|||||||||||.||||||.|||.|:|||:|||||..||....    ..|||||
  Fly   336 NEFVRGHFYGHIDFDLDKTLYFFIAGRYEFGNKGADIFIEALARLNAMLKHEKP----DTTVVAF 396

 Worm   388 LIYPAPANSFNVESLKGQAVTKQLKEAVDRIKEKVGQRIFDICLQGHLPEPEELMSPADNILLKR 452
            ||:|...|:|||:||:|.||.|||::.::.:::.||:|:||.||||::|..::|:...|.:.:||
  Fly   397 LIFPTKTNNFNVDSLRGHAVIKQLRDTINNVQQAVGKRMFDTCLQGNIPNADDLLQKDDLVKIKR 461

 Worm   453 CIMSLHNSSLPPICTHNMIRAD---DPVLESLRRTSLFNKPEDRVKVVFHPEFLSSVSPLIGLDY 514
            |:.::...|:||:.|||:  ||   ||||.|:||..|||...||||:|||||||:|.:||.|:||
  Fly   462 CMFAMQRDSMPPVTTHNV--ADDWNDPVLSSIRRCHLFNSRHDRVKMVFHPEFLTSTNPLFGIDY 524

 Worm   515 EDFVRGCHLGVFPSYYEPWGYTPAECTVMGIPSVSTNLSGFGCFMQEHVEDHEQKGIYVIDRRHK 579
            |:||||||||||||||||||||||||||||||||:||||||||||:||:.|.:..|||::|||:.
  Fly   525 EEFVRGCHLGVFPSYYEPWGYTPAECTVMGIPSVTTNLSGFGCFMEEHISDPKSYGIYIVDRRYI 589

 Worm   580 AAEESVQELAQVMYDFCGQSRRQRIILRNSNEGLSALLDWQNLGVFYRDCRRLALERLHPD-VDK 643
            ..|.|||:|:..|.:|...:||||||.||..|.||.||||:.||::||..|..||:.::|| ||:
  Fly   590 GLENSVQQLSSFMMEFSRLNRRQRIIQRNRTERLSDLLDWRTLGIYYRQARVKALQAVYPDYVDE 654

 Worm   644 I----MRDN------EGKVPSAATSRR----PSIHSSDGED--DE 672
            :    .::|      ..:.||..:||.    ||:|.||.||  ||
  Fly   655 LSLYGSKNNLIFSRPHSEPPSPTSSRHTTPAPSVHGSDDEDSVDE 699

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
gsy-1	NP_496736.1	GT1_Glycogen_synthase_GSY2_like	43..636	CDD:99967	364/603 (60%)
		Glycogen_syn	48..672	CDD:283373	378/651 (58%)
GlyS	NP_731967.2	Glycogen_syn	53..697	CDD:399009	378/649 (58%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C160167503
Domainoid	1	1.000	763	1.000	Domainoid score	I33
eggNOG	1	0.900	-	-		E1_COG0438
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H113557
Inparanoid	1	1.050	785	1.000	Inparanoid score	I264
Isobase	1	0.950	-	0	Normalized mean entropy	S379
OMA	1	1.010	-	-		QHG62683
OrthoDB	1	1.010	-	-		D218500at33208
OrthoFinder	1	1.000	-	-		FOG0003128
OrthoInspector	1	1.000	-	-		oto17710
orthoMCL	1	0.900	-	-		OOG6_103561
Panther	1	1.100	-	-	LDO	PTHR10176
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R2141
SonicParanoid	1	1.000	-	-		X2097
SwiftOrtho	1	1.000	-	-
TreeFam	1	0.960	-	-
	18	17.750