Protein Alignment F44E5.4 and Hsc70-4

DIOPT Version :9

• Sequence 1: NP_496509.1
• Gene: F44E5.4 / 174805
• WormBaseID: WBGene00009691
• Length: 645
• Species: Caenorhabditis elegans
• Sequence 2: NP_001262586.1
• Gene: Hsc70-4 / 41840
• FlyBaseID: FBgn0266599
• Length: 651
• Species: Drosophila melanogaster
• Alignment Length: 659
• Identity: 446/659 - (67%)
• Similarity: 531/659 - (80%)
• Gaps: 22/659 - (3%)

 Worm     1 MSSCKAIGIDLGTTYSCVGIYQNGKVEILANSEGNKTTPSYVAFTDTERLVGDAAKDQAARNPEN 65
            ||...|:||||||||||||::|:|||||:||.:||:||||||||||||||:|||||:|.|.||..
  Fly     1 MSKAPAVGIDLGTTYSCVGVFQHGKVEIIANDQGNRTTPSYVAFTDTERLIGDAAKNQVAMNPTQ 65

 Worm    66 TVFDAKRLIGRRFDESTVQSDCKHWPFGVKGKQGKPVIEVEVKGEKRQFNPEEISAMVLQKMKET 130
            |:|||||||||:||::.||||.|||||.|....|||.|||..|.||:.|.|||||:|||.|||||
  Fly    66 TIFDAKRLIGRKFDDAAVQSDMKHWPFEVVSADGKPKIEVTYKDEKKTFFPEEISSMVLTKMKET 130

 Worm   131 AETYLGHTVKDAVITVPAYFNDSQRQATKDAATIAGLNAIRIINEPTAAALAYGLDKGIQDEKNV 195
            ||.|||.||.:||||||||||||||||||||.||||||.:||||||||||:||||||....|:||
  Fly   131 AEAYLGKTVTNAVITVPAYFNDSQRQATKDAGTIAGLNVLRIINEPTAAAIAYGLDKKAVGERNV 195

 Worm   196 LIFDLGGGTFDVSILSIAEGSIFEVKSTAGDTHLGGEDFDQRMLQHFMNEFKRKTGKDISPNPRA 260
            |||||||||||||||||.:| |||||||||||||||||||.|::.||:.|||||..||::.|.||
  Fly   196 LIFDLGGGTFDVSILSIDDG-IFEVKSTAGDTHLGGEDFDNRLVTHFVQEFKRKHKKDLTTNKRA 259

 Worm   261 IRRLRTACERAKRTLSSSSEACVEVDSLFEGIDLCTKITRARFEELCADLFRKTLEPVEKALRDA 325
            :|||||||||||||||||::|.:|:||||||.|..|.|||||||||.|||||.|::|||||||||
  Fly   260 LRRLRTACERAKRTLSSSTQASIEIDSLFEGTDFYTSITRARFEELNADLFRSTMDPVEKALRDA 324

 Worm   326 KLDKSKIDEVVLVGGSTRVPKIQKLLKDFFNGKELNCSINPDEAVAFGAAVQAAVLSGVKDETIK 390
            |||||.|.::||||||||:||:|:||:|.|||||||.|||||||||:|||||||:|.|.|.:.::
  Fly   325 KLDKSVIHDIVLVGGSTRIPKVQRLLQDLFNGKELNKSINPDEAVAYGAAVQAAILHGDKSQEVQ 389

 Worm   391 DVLLVDVAPLSLGIETAGGVMTNLIDRNTRIPTKACKTFTTYADNQPGVSIQVYEGERAMTRDNH 455
            |:||:||.|||||||||||||:.||.|||.||||..:|||||:||||||.|||||||||||:||:
  Fly   390 DLLLLDVTPLSLGIETAGGVMSVLIKRNTTIPTKQTQTFTTYSDNQPGVLIQVYEGERAMTKDNN 454

 Worm   456 RLGTFELSGIPPAPRGVPQIEVTFDIDANGILNVSAEDKSTGKSNRITIQNEKGRLTQSDIDRMV 520
            .||.||||||||||||||||||||||||||||||:|.::||.|.|:|||.|:||||::.||:|||
  Fly   455 LLGKFELSGIPPAPRGVPQIEVTFDIDANGILNVTALERSTNKENKITITNDKGRLSKEDIERMV 519

 Worm   521 HEAKQFEKEDGEQRERVQARNQLEAYAFQIKQALDE--YSSKLSTEDASRAKEAVDETLRWLDSN 583
            :||:::..||.:|:|.:.|:|.||:|.|.:|..|||  ..:|:|..|.:...:..:||::|||:|
  Fly   520 NEAEKYRNEDEKQKETIAAKNGLESYCFNMKATLDEDNLKTKISDSDRTTILDKCNETIKWLDAN 584

 Worm   584 SLAEKDEIEAKDKELKSVCQSILTKMHQS------------GQSSASAGCAGNPGTAGFNPNNYP 636
            .||:|:|.|.:.|||:.||..|:||::|.            |....:||.||..|..|
  Fly   585 QLADKEEYEHRQKELEGVCNPIITKLYQGAGFPPGGMPGGPGGMPGAAGAAGAAGAGG------- 642

 Worm   637 QGPTVEEVD 645
            .|||:||||
  Fly   643 AGPTIEEVD 651

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
F44E5.4	NP_496509.1	PTZ00009	1..645	CDD:240227	444/657 (68%)
		HSPA1-2_6-8-like_NBD	6..382	CDD:212675	287/375 (77%)
Hsc70-4	NP_001262586.1	PTZ00009	1..612	CDD:240227	431/611 (71%)
		HSPA1-2_6-8-like_NBD	6..381	CDD:212675	287/375 (77%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0443
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	1	0.950	-	0	Normalized mean entropy	S49
OMA	1	1.010	-	-		QHG53894
OrthoDB	1	1.010	-	-		D180577at33208
OrthoFinder	1	1.000	-	-		FOG0000049
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100083
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	7	6.680