Protein Alignment DLX4 and tin

DIOPT Version :10

• Sequence 1: NP_612138.1
• Gene: DLX4 / 1748
• HGNCID: 2917
• Length: 240
• Species: Homo sapiens
• Sequence 2: NP_524433.1
• Gene: tin / 42536
• FlyBaseID: FBgn0004110
• Length: 416
• Species: Drosophila melanogaster
• Alignment Length: 276
• Identity: 70/276 - (25%)
• Similarity: 98/276 - (35%)
• Gaps: 94/276 - (34%)

Human    28 AAAYPLGLSPTTAASPNLSYSRPYGHLLSY------------------------PYTEPA----- 63
            |:||.:..|...|.:...:|..|..:..:|                        ||..|:
  Fly   154 ASAYNMSASQFYAGASATAYQTPATYNYNYAGSGEVYGGATPSAVGIKSEYIPTPYVTPSPTLDL 218

Human    64 NPGDSYLSCQQPA------ALSQPLCGPAEHPQELEA---------DSEKPRLSPEPSERRPQA- 112
            |......|.|.|.      .|||.|...|.:...|.:         ..:..:::...||.|..:
  Fly   219 NSSAEVDSLQAPTQKLCVNPLSQRLMETASNSSSLRSIYGSDEGAKKKDNSQVTSSRSELRKNSI 283

Human   113 --------------PAKKLRKPRTIYSSLQLQHLNQRFQHTQYLALPERAQLAAQLGLTQTQVKI 163
                          |..| ||||.::|..|:..|..||:..:||...||..:|.:|.|:.|||||
  Fly   284 SGNSNPGSNSGSTKPRMK-RKPRVLFSQAQVLELECRFRLKKYLTGAEREIIAQKLNLSATQVKI 347

Human   164 WFQNKRSKYK----------KLLKQNSGGQEGDFPGRTFSVSPCS--PPLPS--LWDLPKAGTLP 214
            ||||:|.|.|          |.||..|...:          ||.|  ||:|:  :|.       |
  Fly   348 WFQNRRYKSKRGDIDCEGIAKHLKLKSEPLD----------SPTSLPPPIPNHVMWP-------P 395

Human   215 TSGYGNSFGAWYQHHS 230
            |......   ..|||:
  Fly   396 TMQQSQQ---QQQHHA 408

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
DLX4	NP_612138.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	80..120		10/63 (16%)
		Homeodomain	118..174	CDD:459649	28/65 (43%)
tin	NP_524433.1	Homeodomain	302..358	CDD:459649	27/55 (49%)