Protein Alignment DLX4 and Hmx

DIOPT Version :10

• Sequence 1: NP_612138.1
• Gene: DLX4 / 1748
• HGNCID: 2917
• Length: 240
• Species: Homo sapiens
• Sequence 2: NP_001262674.1
• Gene: Hmx / 42110
• FlyBaseID: FBgn0264005
• Length: 718
• Species: Drosophila melanogaster
• Alignment Length: 301
• Identity: 74/301 - (24%)
• Similarity: 104/301 - (34%)
• Gaps: 93/301 - (30%)

Human     4 LPCPLPGRDASKAVFPDLAPVPSVAAAYPLGLSPTTAASPNLSYSRPYGHLLSYPYTEPANPGDS 68
            ||...|..|:|.....:..|.|:..:......:..|.||.|.:...|..|.| :|...|......
  Fly   306 LPFHSPTHDSSSTNTTENPPSPTSMSPNNNNNNSNTTASSNQASKSPSHHPL-HPLYHPLGSQQQ 369

Human    69 YLSCQQ----PAALSQPLCGPAEHPQE-------------------------------------L 92
            ....||    |.....|.....:||.:                                     .
  Fly   370 QQQQQQHQQHPQQQQHPQQQQQQHPHQPTTPTSSSSSGGGSSLTHHPHPHLTGSHGGYLLPSSSN 434

Human    93 EADSEKPRLSPE------PSERRPQAP-----AKKLRKPRTIYSSLQLQHLNQRFQHTQYLALPE 146
            |:|.|...:..|      ||:  ..:|     :|:.:|.||::|..|:..|...|...:||:..|
  Fly   435 ESDEEGEEIIEEDDGTDGPSD--SSSPHGDGNSKRKKKTRTVFSRAQVFQLESTFDLKRYLSSSE 497

Human   147 RAQLAAQLGLTQTQVKIWFQNKRSKYKKLLK------------------------QNSGGQEGDF 187
            ||.|||.|.||:|||||||||:|:|:|:.|.                        .:.|...|..
  Fly   498 RAGLAASLRLTETQVKIWFQNRRNKWKRQLAAELEAANMANMAHAAQRLVRVPVLYHDGTTAGFV 562

Human   188 P------------GRTFSVSPCSPPLPSLWDLPKAGTLPTS 216
            |            ....:.||..|||.||  : ..|.|.|:
  Fly   563 PPPPPHHHPMQYYAAARNTSPPRPPLSSL--VXGVGCLATA 601

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
DLX4	NP_612138.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	80..120		11/87 (13%)
		Homeodomain	118..174	CDD:459649	29/55 (53%)
Hmx	NP_001262674.1	Homeodomain	469..525	CDD:459649	29/55 (53%)