Protein Alignment DLX4 and Dll

DIOPT Version :10

• Sequence 1: NP_612138.1
• Gene: DLX4 / 1748
• HGNCID: 2917
• Length: 240
• Species: Homo sapiens
• Sequence 2: NP_001137759.1
• Gene: Dll / 37973
• FlyBaseID: FBgn0000157
• Length: 347
• Species: Drosophila melanogaster
• Alignment Length: 244
• Identity: 99/244 - (40%)
• Similarity: 123/244 - (50%)
• Gaps: 51/244 - (20%)

Human     8 LPGRDASKAVFPDLAPVPSVAAAY-----------PLGLSPTTAASPNLSYSRPYGHLLSYPYTE 61
            :||    |:.|.:|.  ...||.|           |.|...:...||..:        |.||:
  Fly    28 IPG----KSAFVELQ--QHAAAGYGGIRSTYQHFGPQGGQDSGFPSPRSA--------LGYPF-- 76

Human    62 PANPGDSYLSCQQPAALSQPLCGPAEHPQELEADSEKPRLSPEPSERRPQAPAKKLRKPRTIYSS 126
            |....:|| |.....:.:.|...|   |::..:.|:|    .|.|..|.....||:|||||||||
  Fly    77 PPMHQNSY-SGYHLGSYAPPCASP---PKDDFSISDK----CEDSGLRVNGKGKKMRKPRTIYSS 133

Human   127 LQLQHLNQRFQHTQYLALPERAQLAAQLGLTQTQVKIWFQNKRSKYKKLLK------QNSG---G 182
            ||||.||:|||.||||||||||:|||.||||||||||||||:||||||::|      .|||   |
  Fly   134 LQLQQLNRRFQRTQYLALPERAELAASLGLTQTQVKIWFQNRRSKYKKMMKAAQGPGTNSGMPLG 198

Human   183 QEGDFPGRTFSVSPCSPPLPS---LW-DLPKAGTLP---TSGYGNSFGA 224
            ..|..||:.......|..|.:   || .|...|||.   ::|..|..|:
  Fly   199 GGGPNPGQHSPNQMHSGELANGRFLWAALETNGTLALVHSTGGNNGGGS 247

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
DLX4	NP_612138.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	80..120		11/39 (28%)
		Homeodomain	118..174	CDD:459649	49/55 (89%)
Dll	NP_001137759.1	Homeodomain	125..181	CDD:459649	49/55 (89%)