Protein Alignment DLX4 and en

DIOPT Version :10

• Sequence 1: NP_612138.1
• Gene: DLX4 / 1748
• HGNCID: 2917
• Length: 240
• Species: Homo sapiens
• Sequence 2: NP_523700.2
• Gene: en / 36240
• FlyBaseID: FBgn0000577
• Length: 552
• Species: Drosophila melanogaster
• Alignment Length: 207
• Identity: 61/207 - (29%)
• Similarity: 92/207 - (44%)
• Gaps: 53/207 - (25%)

Human     2 TSLPCPLPGRDASKAVFPDLAPVPSVAAAYPLGLSPTTAASPNLSYSRPYGHL--------LSYP 58
            :||..|.|..:||     .::...|||.:.....|..::|:.:|: |.|...|        .|.|
  Fly   324 SSLASPPPASNAS-----TISSTSSVATSSSSSSSGCSSAASSLN-SSPSSRLGASGSGVNASSP 382

Human    59 YTEPANPGDSYLSCQQPAALSQPLCGPAEHPQELEAD-----------------------SEKPR 100
            ..:|..|         |:|:|:.  ...|...:..::                       |::|
  Fly   383 QPQPIPP---------PSAVSRD--SGMESSDDTRSETGSTTTEGGKNEMWPAWVYCTRYSDRP- 435

Human   101 LSPEPSERRPQAPAKKL---RKPRTIYSSLQLQHLNQRFQHTQYLALPERAQLAAQLGLTQTQVK 162
             |..|..|||:.|..|.   ::|||.:||.||..|.:.|...:||....|.||:::|||.:.|:|
  Fly   436 -SSGPRYRRPKQPKDKTNDEKRPRTAFSSEQLARLKREFNENRYLTERRRQQLSSELGLNEAQIK 499

Human   163 IWFQNKRSKYKK 174
            |||||||:|.||
  Fly   500 IWFQNKRAKIKK 511

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
DLX4	NP_612138.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	80..120		10/65 (15%)
		Homeodomain	118..174	CDD:459649	27/55 (49%)
en	NP_523700.2	Homeodomain	455..511	CDD:459649	27/55 (49%)
		Engrail_1_C_sig	512..542	CDD:431338	61/207 (29%)