Protein Alignment DLX4 and H2.0

DIOPT Version :10

• Sequence 1: NP_612138.1
• Gene: DLX4 / 1748
• HGNCID: 2917
• Length: 240
• Species: Homo sapiens
• Sequence 2: NP_523488.2
• Gene: H2.0 / 33841
• FlyBaseID: FBgn0001170
• Length: 418
• Species: Drosophila melanogaster
• Alignment Length: 279
• Identity: 67/279 - (24%)
• Similarity: 104/279 - (37%)
• Gaps: 71/279 - (25%)

Human     7 PLPGRDASKAVFPD--------LAPVPSVAAAYPLGLSPTTAASPNLSYSRPYGHLLSYPYTEPA 63
            |..|.|   .:||.        |.|.|..||.:.....||.|.:..|.:.:.........:....
  Fly   143 PFVGLD---KLFPGPYMDYKSVLRPTPIRAAEHAAPTYPTLATNALLRFHQHQKQQHQQHHHHQH 204

Human    64 NPGDSYLSCQQP---AALSQPLCGPAEHPQELEADSEKPR-LSPEPSER---RPQAPA------- 114
            :|...:...:.|   :..:..|..|......|:...::.| |...|.:.   .|.:||
  Fly   205 HPKHLHQQHKPPPHNSTTASALLAPLHSLTSLQLTQQQQRFLGKTPQQLLDIAPTSPAAAAAATS 269

Human   115 -----------------------KKLRKPRTIYSSLQLQHLNQRFQHTQYLALPERAQLAAQLGL 156
                                   :|....|.::|:||.:.|..:||..:|:..|:|.:|||:|.|
  Fly   270 QNGAHGHGGGNGQGNASAGSNGKRKRSWSRAVFSNLQRKGLEIQFQQQKYITKPDRRKLAARLNL 334

Human   157 TQTQVKIWFQNKRSKYKKLLKQNSGGQEGDFPGRTFSVSPCSPPLPSLWDLPKAG----TLPTSG 217
            |..|||:||||:|.|::...:....|||..               ||.  :|::|    |...||
  Fly   335 TDAQVKVWFQNRRMKWRHTRENLKSGQEKQ---------------PSA--VPESGGVFKTSTPSG 382

Human   218 YGNSFGAWYQHHSSDVLAS 236
            .|....|  ..:|||..:|
  Fly   383 DGTPQEA--LDYSSDSCSS 399

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
DLX4	NP_612138.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	80..120		10/73 (14%)
		Homeodomain	118..174	CDD:459649	25/55 (45%)
H2.0	NP_523488.2	Homeodomain	292..352	CDD:459649	26/59 (44%)