Protein Alignment DLX3 and CG34367

DIOPT Version :10

• Sequence 1: NP_005211.1
• Gene: DLX3 / 1747
• HGNCID: 2916
• Length: 287
• Species: Homo sapiens
• Sequence 2: NP_001097140.1
• Gene: CG34367 / 5740879
• FlyBaseID: FBgn0085396
• Length: 420
• Species: Drosophila melanogaster
• Alignment Length: 302
• Identity: 76/302 - (25%)
• Similarity: 119/302 - (39%)
• Gaps: 84/302 - (27%)

Human    13 LTDISSSLS-------------CHAGSKD-------SPTLPESSV----------TDLGYYSAPQ 47
            :||:|.|.|             .|:..::       ||||.:::|          .||...|.|:
  Fly    69 ITDLSVSESNTILAIDPEPTEESHSQREEHVETYSLSPTLHKAAVEPKPKNWLISEDLDVDSQPE 133

Human    48 HDYYSGQPYGQTVNPYTYHHQFNLNGLAGTGAYSPKSEYTYGASYRQYGAYREQPLPAQDPVSVK 112
            ....||.|.. ::...|..        :.|...:|                 ::||..::.||
  Fly   134 DPKMSGLPTA-SITECTED--------SNTPKLAP-----------------DKPLLPEECVS-- 170

Human   113 EEPE--------AEVRMVNGKPKKVRKPRTIYSSYQLAALQRRFQKAQYLALPERAELAAQLGLT 169
            .||.        .:..:||   .|.|:.||.::..||..|:|.|::..|.....|.||:.:|||:
  Fly   171 PEPSRNREHCDPLDTSLVN---TKQRRSRTNFTLDQLNELERLFEETHYPDAFMREELSQRLGLS 232

Human   170 QTQVKIWFQNRRSKFKK----LYKNGEVPLEHSPNNSDSMACNSPP---SPALWDTSSHSTPAPA 227
            :.:|::||||||:|.:|    ::|...|.....|..:....|...|   ..||..:|..|.||.|
  Fly   233 EARVQVWFQNRRAKCRKHENQMHKGFLVGSRSPPIATPLEPCRVAPYVSLAALRSSSVPSHPAAA 297

Human   228 RSQLPPPLPYSASPS-----YLDDPTNSWYHAQNLSGPHLQQ 264
            .|..|.....|.:.|     .:|.|.|   |...:|...::|
  Fly   298 TSSNPQAPGVSGTSSSGKVVTVDSPHN---HNPAISRSAIKQ 336

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
DLX3	NP_005211.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	20..39		7/48 (15%)
		DLL_N	27..107	CDD:463567	17/96 (18%)
		COG5576	<109..232	CDD:227863	44/137 (32%)
		homeobox	129..188		24/62 (39%)
		Homeodomain	130..186	CDD:459649	23/55 (42%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	195..287		20/78 (26%)
CG34367	NP_001097140.1	Homeodomain	193..249	CDD:459649	23/55 (42%)
		OAR	392..410	CDD:461067