Protein Alignment DLX3 and Drgx

DIOPT Version :10

• Sequence 1: NP_005211.1
• Gene: DLX3 / 1747
• HGNCID: 2916
• Length: 287
• Species: Homo sapiens
• Sequence 2: NP_001097075.2
• Gene: Drgx / 5740176
• FlyBaseID: FBgn0085369
• Length: 587
• Species: Drosophila melanogaster
• Alignment Length: 251
• Identity: 58/251 - (23%)
• Similarity: 95/251 - (37%)
• Gaps: 71/251 - (28%)

Human    82 PKSEYTYGASYRQYGAYREQPLPAQDPVSVKEEPEAEVRMVNGKPKKVRKPRTIYSSYQLAALQR 146
            |..:|.:.|:: .|.:|...| ...|...|:              :|.|:.||.::..||..|:.
  Fly    21 PTLDYPFAATH-PYTSYSYHP-AIHDETFVR--------------RKQRRNRTTFTLQQLEELET 69

Human   147 RFQKAQYLALPERAELAAQLGLTQTQVKIWFQNRRSKFKKLYK---------NGEVPLEHSPNNS 202
            .|.:..|..:..|.:||.::.||:.:|::||||||:|::|..:         |||     |.::.
  Fly    70 AFAQTHYPDVFTREDLAMKINLTEARVQVWFQNRRAKWRKAERLKDEQRKRENGE-----SSSSL 129

Human   203 DSMACNSPPSPAL-WDTSSHSTPAPARSQLPPPL---------------PYSASPS---YLDDPT 248
            |.:..:...||.: .:........|.|.:...||               .:|.||.   :||...
  Fly   130 DKLHDSRESSPDITGEIDDDMDDLPPRQRSHSPLANGQMEQQHSHSHSHSHSRSPGGGMHLDSSD 194

Human   249 NSWYHAQN--LSGPHLQQQ--------PPQPATLHH------------ASPGPPPN 282
            |....:.|  .:.||...|        .|.|:.:|.            ..|..|.|
  Fly   195 NERPLSSNQLTATPHSASQSLGSISAGSPSPSGMHREREHTPLVGGGGQGPSSPSN 250

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
DLX3	NP_005211.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	20..39
		DLL_N	27..107	CDD:463567	6/24 (25%)
		COG5576	<109..232	CDD:227863	33/132 (25%)
		homeobox	129..188		22/58 (38%)
		Homeodomain	130..186	CDD:459649	21/55 (38%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	195..287		24/129 (19%)
Drgx	NP_001097075.2	Homeodomain	53..109	CDD:459649	21/55 (38%)
		OAR	428..446	CDD:461067