Protein Alignment DLX3 and ro

DIOPT Version :10

• Sequence 1: NP_005211.1
• Gene: DLX3 / 1747
• HGNCID: 2916
• Length: 287
• Species: Homo sapiens
• Sequence 2: NP_524521.1
• Gene: ro / 43234
• FlyBaseID: FBgn0003267
• Length: 350
• Species: Drosophila melanogaster
• Alignment Length: 269
• Identity: 71/269 - (26%)
• Similarity: 101/269 - (37%)
• Gaps: 43/269 - (15%)

Human    25 GSKDSPTLPESSV-TDLGYYSAPQHDYYS-GQPYGQTVNPYTYHHQFNLNGLAGTGAYSPKSEYT 87
            ||..||.:..|.. |.|..|  |.:|:|. .:.|.|  :|...|.|.:.:..........|..|.
  Fly    83 GSVSSPDISISDERTSLAAY--PAYDFYGHAKDYPQ--HPSQQHQQHHHHHHHPPQLVHQKLSYV 143

Human    88 YGASYRQYGAYREQPLPAQDPVSVKEEPE---------AEVRMVNGKPKKVRKPRTIYSSYQLAA 143
            ........|......||...|.....:|.         |..|...|:.   |:.||.:|:.|...
  Fly   144 SPPPAIAAGGAANPVLPHAFPAGFPSDPHFSAGFSAFLARRRRKEGRQ---RRQRTTFSTEQTLR 205

Human   144 LQRRFQKAQYLALPERAELAAQLGLTQTQVKIWFQNRRSKFKKL--------YKNGEVPLEHSPN 200
            |:..|.:.:|::...|.|||..|.||:||:||||||||:|.|::        |:|..|......:
  Fly   206 LEVEFHRNEYISRSRRFELAETLRLTETQIKIWFQNRRAKDKRIEKAQIDQHYRNFVVANGFMSS 270

Human   201 NSDSMACNSPPSPALWDT---------SSHSTPAPARSQLPPPLPYSASPSYLDDPTNSWYHAQN 256
            .....|...||.......         ::.:|||    .||......|:...:||.    :..|.
  Fly   271 IMGQAATTMPPGGVTGGVAVGVGLNYYAAAATPA----ALPKDNTQDANFIDIDDQ----FQRQQ 327

Human   257 LSGPHLQQQ 265
            ......|||
  Fly   328 QQKQQQQQQ 336

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
DLX3	NP_005211.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	20..39		5/14 (36%)
		DLL_N	27..107	CDD:463567	19/81 (23%)
		COG5576	<109..232	CDD:227863	40/148 (27%)
		homeobox	129..188		27/66 (41%)
		Homeodomain	130..186	CDD:459649	26/55 (47%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	195..287		15/80 (19%)
ro	NP_524521.1	Homeodomain	196..248	CDD:459649	24/51 (47%)