Protein Alignment DLX3 and exex

DIOPT Version :10

• Sequence 1: NP_005211.1
• Gene: DLX3 / 1747
• HGNCID: 2916
• Length: 287
• Species: Homo sapiens
• Sequence 2: NP_648164.1
• Gene: exex / 38884
• FlyBaseID: FBgn0041156
• Length: 525
• Species: Drosophila melanogaster
• Alignment Length: 266
• Identity: 63/266 - (23%)
• Similarity: 104/266 - (39%)
• Gaps: 84/266 - (31%)

Human    18 SSLSCHAGSKDSPTLPESSVTDLGYYSAPQHDYYSGQPYGQTVNPYTYHHQFNLNGLAGTGAYSP 82
            ::.|...|..:...|  ..:.|...|.:|..|..|     ::.:|.:.|.        .:...||
  Fly   274 AAASAAGGISEQEAL--QRIRDSREYDSPSPDGMS-----RSESPTSSHR--------SSPPISP 323

Human    83 KSE---YTYGASYRQYGAYR--------EQPLPAQDPVSVKEEP---------------EAEVRM 121
            ..|   ..:||.:.|:.:.|        ::|:|...|:..::.|               .|..|.
  Fly   324 GCEDQQQPHGALHPQHLSMRMSDFHDEFKKPIPPHSPIRPQDFPLYAGGHPYQLLAQGGSAFHRP 388

Human   122 V--NGKP-----------------------------------------KKVRKPRTIYSSYQLAA 143
            :  :|||                                         .|.|:|||.::|.||..
  Fly   389 LDPSGKPIPIPMGHNFMPSQLQFEFLARAGMLHHRIPELAAYPHHAILGKTRRPRTAFTSQQLLE 453

Human   144 LQRRFQKAQYLALPERAELAAQLGLTQTQVKIWFQNRRSKFKKLYKNGEVPLEHSPNNSDSMACN 208
            |:::|::.:||:.|:|.|:|:.|.|::|||||||||||.|:|:..|..:...|.:..|.......
  Fly   454 LEKQFKQNKYLSRPKRFEVASGLMLSETQVKIWFQNRRMKWKRSKKAQQEAKERAKANQQQQQQQ 518

Human   209 SPPSPA 214
            ..||.|
  Fly   519 QTPSAA 524

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
DLX3	NP_005211.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	20..39		3/18 (17%)
		DLL_N	27..107	CDD:463567	17/90 (19%)
		COG5576	<109..232	CDD:227863	43/164 (26%)
		homeobox	129..188		30/58 (52%)
		Homeodomain	130..186	CDD:459649	29/55 (53%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	195..287		5/20 (25%)
exex	NP_648164.1	Homeodomain	440..496	CDD:459649	29/55 (53%)