Protein Alignment DLX3 and inv

DIOPT Version :10

• Sequence 1: NP_005211.1
• Gene: DLX3 / 1747
• HGNCID: 2916
• Length: 287
• Species: Homo sapiens
• Sequence 2: NP_523699.3
• Gene: inv / 36239
• FlyBaseID: FBgn0001269
• Length: 576
• Species: Drosophila melanogaster
• Alignment Length: 218
• Identity: 60/218 - (27%)
• Similarity: 88/218 - (40%)
• Gaps: 58/218 - (26%)

Human    17 SSSLS--CHAGSKDSPTLPESSVTDLGYYSAPQHDYYSGQPYGQTVNPYTYHHQFNLNGLAGTGA 79
            ||||:  |...:..:.|...||.|:.           ||.|.....:|..      ..|...|||
  Fly   355 SSSLANICSNSNDSNSTATSSSTTNT-----------SGAPVDLVKSPPP------AAGAGATGA 402

Human    80 YSPKSEYTYGA-----SYRQYGAYREQPLPAQDPVSVKEEPEA----------------EVRMVN 123
             |.||....|.     ::.....|.::|...:.|.:.|.:..|                |.....
  Fly   403 -SGKSGEDSGTPIVWPAWVYCTRYSDRPSSGRSPRARKPKKPATSSSAAGGGGGGVEKGEAADGG 466

Human   124 GKPKKVRKPRTIYSSYQLAALQRRFQKAQYLALPERAELAAQLGLTQTQVKIWFQNRRSKFKK-- 186
            |.|:. ::|||.:|..|||.|:..|.:.:||....|.:|:.:|||.:.|:||||||:|:|.||
  Fly   467 GVPED-KRPRTAFSGTQLARLKHEFNENRYLTEKRRQQLSGELGLNEAQIKIWFQNKRAKLKKSS 530

Human   187 --------------LYKNGEVPL 195
                          ||.:..:||
  Fly   531 GTKNPLALQLMAQGLYNHSTIPL 553

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
DLX3	NP_005211.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	20..39		5/20 (25%)
		DLL_N	27..107	CDD:463567	18/84 (21%)
		COG5576	<109..232	CDD:227863	36/119 (30%)
		homeobox	129..188		27/74 (36%)
		Homeodomain	130..186	CDD:459649	25/55 (45%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	195..287		1/1 (100%)
inv	NP_523699.3	Homeodomain	472..528	CDD:459649	25/55 (45%)
		Engrail_1_C_sig	529..554	CDD:431338	4/25 (16%)