Protein Alignment DLX3 and scro

DIOPT Version :10

• Sequence 1: NP_005211.1
• Gene: DLX3 / 1747
• HGNCID: 2916
• Length: 287
• Species: Homo sapiens
• Sequence 2: NP_001015473.1
• Gene: scro / 3355151
• FlyBaseID: FBgn0287186
• Length: 468
• Species: Drosophila melanogaster
• Alignment Length: 244
• Identity: 59/244 - (24%)
• Similarity: 93/244 - (38%)
• Gaps: 86/244 - (35%)

Human    33 PESSVTDLGYYSAPQHDYYSGQPYGQTVN--------------PYTYHHQFNLNGLAGTGAYSPK 83
            |..:::..|:|:..::   |...||.|.|              ..|..|..|::|||.......|
  Fly   183 PTDNLSLAGHYTDMRN---SASWYGSTANDPRFAISRLMSSSASGTMSHMGNMSGLAACSVSDSK 244

Human    84 SEYTYGASYRQYGAYREQPLPAQDPVSVKEEPEAEVRMVNGKPKKVRKPRTIYSSYQLAALQRRF 148
                                |.|.|::.:                 ||.|.:::..|:..|:|||
  Fly   245 --------------------PLQFPLAQR-----------------RKRRVLFTQAQVYELERRF 272

Human   149 QKAQYLALPERAELAAQLGLTQTQVKIWFQNRRSKFKKLYKNGEVPLEHSPNNSDSMACNSPPSP 213
            ::.:||:.|||..||:.:.||.|||||||||.|.|.|:..|                      ..
  Fly   273 KQQRYLSAPEREHLASLIHLTPTQVKIWFQNHRYKCKRQAK----------------------EK 315

Human   214 ALWDTSSHSTPAPARSQLPPPL------PYSASPSYLDDPTNSWYHAQN 256
            |:.:.:.|:.||.:..::..|:      |.|.:.|    .:.|..|..|
  Fly   316 AMAEQNQHNQPASSPRRVAVPVLVKDGKPCSGNNS----SSQSQQHGTN 360

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
DLX3	NP_005211.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	20..39		1/5 (20%)
		DLL_N	27..107	CDD:463567	16/87 (18%)
		COG5576	<109..232	CDD:227863	34/122 (28%)
		homeobox	129..188		29/58 (50%)
		Homeodomain	130..186	CDD:459649	28/55 (51%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	195..287		11/68 (16%)
scro	NP_001015473.1	Homeodomain	254..310	CDD:459649	28/55 (51%)