Protein Alignment DLX3 and B-H2

DIOPT Version :10

• Sequence 1: NP_005211.1
• Gene: DLX3 / 1747
• HGNCID: 2916
• Length: 287
• Species: Homo sapiens
• Sequence 2: NP_523386.1
• Gene: B-H2 / 32723
• FlyBaseID: FBgn0004854
• Length: 645
• Species: Drosophila melanogaster
• Alignment Length: 233
• Identity: 65/233 - (27%)
• Similarity: 92/233 - (39%)
• Gaps: 82/233 - (35%)

Human   127 KKVRKPRTIYSSYQLAALQRRFQKAQYLALPERAELAAQLGLTQTQVKIWFQNRRSK-------- 183
            ||.||.||.::.:||..|::.|::.:||::.:|.|||.:|.|:..|||.|:||||:|
  Fly   378 KKQRKARTAFTDHQLQTLEKSFERQKYLSVQDRMELANKLELSDCQVKTWYQNRRTKWKRQTAVG 442

Human   184 ------------FKKLYKNGEVP-----------LEHSPNNSD-------------SMACNSPPS 212
                        |::|| .|..|           ...||:.:.             :.|...|..
  Fly   443 LELLAEAGNYAAFQRLY-GGATPYLSAWPYAAAAAAQSPHGATPSAIDIYYRQAAAAAAMQKPSL 506

Human   213 PALWDTSSHSTPAPARS--QLPPPLPYSASPSYLDDPTNSWYH------AQNLSGPHLQQQPP-- 267
            ||.:.....|.| |..|  .:|.|.|..|:|..      |.|:      |.:......|||||
  Fly   507 PASYRMYQSSIP-PGMSLPGMPAPPPPGAAPML------SGYYAAAAAAAASAGAQQQQQQPPAA 564

Human   268 --QPATLHHA------------------SPGPPPNPGA 285
              .|||...|                  :|.||.|||:
  Fly   565 SRSPATSQSANSEADCERTSSSSRQRLITPSPPLNPGS 602

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
DLX3	NP_005211.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	20..39
		DLL_N	27..107	CDD:463567
		COG5576	<109..232	CDD:227863	42/150 (28%)
		homeobox	129..188		26/78 (33%)
		Homeodomain	130..186	CDD:459649	26/75 (35%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	195..287		33/134 (25%)
B-H2	NP_523386.1	Homeodomain	381..437	CDD:459649	25/55 (45%)