Protein Alignment DLX3 and vnd

DIOPT Version :10

• Sequence 1: NP_005211.1
• Gene: DLX3 / 1747
• HGNCID: 2916
• Length: 287
• Species: Homo sapiens
• Sequence 2: NP_476786.2
• Gene: vnd / 31003
• FlyBaseID: FBgn0261930
• Length: 723
• Species: Drosophila melanogaster
• Alignment Length: 297
• Identity: 72/297 - (24%)
• Similarity: 116/297 - (39%)
• Gaps: 64/297 - (21%)

Human    16 ISSSLSCHAGSKDSPTLPESSVTDLGYYSAPQHDYYSGQPYGQTVNPYTYH--HQFNLNGLAGTG 78
            :|.....::.|.||..|   ||.|      ..|..:.....|......|.|  |. |.|......
  Fly   438 LSGDYKSYSRSADSDAL---SVGD------ALHTLHGSSGNGSAGGAPTAHALHN-NNNNTTNNN 492

Human    79 AYSPKSEYTYGASYRQYGAYREQPLPAQDPVSVKEEPE----AEVRMVNGKPKKVRKPRTIYSSY 139
            .:|.|:|...||......:..|..:  ::.:...::.:    .:....:|.|.|.||.|.:::..
  Fly   493 NHSLKAEGINGAGSGHDDSLNEDGI--EEDIDDVDDADGSGGGDANGSDGLPNKKRKRRVLFTKA 555

Human   140 QLAALQRRFQKAQYLALPERAELAAQLGLTQTQVKIWFQNRRSKFKK------------------ 186
            |...|:|||::.:||:.|||..||:.:.||.|||||||||.|.|.|:
  Fly   556 QTYELERRFRQQRYLSAPEREHLASLIRLTPTQVKIWFQNHRYKTKRAQNEKGYEGHPGLLHGHA 620

Human   187 -------------------LYKNGEVPL-EHSPNNSDSMACNSPPSPALWDTSSHSTPAPARSQL 231
                               |.:||:..| :.|...:|.::.:|..:.|:.:.::|...|     |
  Fly   621 THPHHPSALPSPRRVAVPVLVRNGKPCLGDSSKLGADCVSVSSATATAMQNAAAHHLVA-----L 680

Human   232 PPPLPY---SASPSYLDDPTNSWYHAQNLSGPHLQQQ 265
            .....|   :|:.:.|....::..||.....||...|
  Fly   681 NGAAAYQHAAAAAAGLHAHAHAHAHAHGHGHPHAHAQ 717

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
DLX3	NP_005211.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	20..39		6/18 (33%)
		DLL_N	27..107	CDD:463567	19/81 (23%)
		COG5576	<109..232	CDD:227863	42/164 (26%)
		homeobox	129..188		29/95 (31%)
		Homeodomain	130..186	CDD:459649	28/55 (51%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	195..287		16/75 (21%)
vnd	NP_476786.2	Homeodomain	546..602	CDD:459649	28/55 (51%)