DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Mos and slpr

DIOPT Version :9

Sequence 1:	NP_064405.2	Gene:	Mos / 17451	MGIID:	97052	Length:	343	Species:	Mus musculus
Sequence 2:	NP_001188558.1	Gene:	slpr / 44111	FlyBaseID:	FBgn0030018	Length:	1155	Species:	Drosophila melanogaster

Alignment Length:	317	Identity:	83/317 - (26%)
Similarity:	149/317 - (47%)	Gaps:	78/317 - (24%)

- Green bases have known domain annotations that are detailed below.

Mouse    50 PRRLAWFSIDWEQVCLMHRLGSGGFGSVYKATYHGVPVAIKQVNKCTKDLRASQRS--------F 106
            |..:.:..:|.::|     :|||||..|::..|.|..||||..::..:|.....|.        |
  Fly   121 PHEIEYNELDIKEV-----IGSGGFCKVHRGYYDGEEVAIKIAHQTGEDDMQRMRDNVLQEAKLF 180

Mouse   107 WAELNIARLRHDNI--VRVVAASTRTPEDSNSLGTIIMEFGGNVTLHQVIYGATRSPEPLSCREQ 169
            ||      |:|:||  :|.|..:|:.        .::||:....:|::::.|.. .|:.|
  Fly   181 WA------LKHENIAALRGVCLNTKL--------CLVMEYARGGSLNRILAGKI-PPDVL----- 225

Mouse   170 LSLGKCLKYSLDVVNGLLFLHSQ---SILHLDLKPANILISE--------QDVCKISDFGCSQKL 223
                  :.:::.:..|:.:||::   ||:|.|||.:|:||.|        |...||:|||.::::
  Fly   226 ------VNWAIQIARGMNYLHNEAPMSIIHRDLKSSNVLIYEAIEGNHLQQKTLKITDFGLAREM 284

Mouse   224 QDLRCRQASPHHIGGTYTHQAPEILKGEIATPKADIYSFGITLWQMTTREVPYSG-EPQYVQYAV 287
            .:.:...|:     |||....||::.....:..:|::|:|:.||::.|.|.||.| :|..|.|.|
  Fly   285 YNTQRMSAA-----GTYAWMPPEVISVSTYSKFSDVWSYGVLLWELITGETPYKGFDPLSVAYGV 344

Mouse   288 VAYNLR-------PSLAGAVFTASLTGKTLQNIIQSCWEARALQRPGAELLQRDLKA 337
            ....|.       |...||             :::|||:....:|||.:.:.:.|::
  Fly   345 AVNTLTLPIPKTCPETWGA-------------LMKSCWQTDPHKRPGFKEILKQLES 388

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Mos	NP_064405.2	STKc_Mos	59..335	CDD:270881	81/304 (27%)
slpr	NP_001188558.1	SH3_MLK	47..104	CDD:212809
		TyrKc	129..386	CDD:197581	81/305 (27%)
		STKc_MLK	134..389	CDD:270963	81/304 (27%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG0192
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810