DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment R09D1.12 and btl

DIOPT Version :9

Sequence 1:	NP_496025.2	Gene:	R09D1.12 / 174501	WormBaseID:	WBGene00011168	Length:	455	Species:	Caenorhabditis elegans
Sequence 2:	NP_001014583.1	Gene:	btl / 39564	FlyBaseID:	FBgn0285896	Length:	1052	Species:	Drosophila melanogaster

Alignment Length:	431	Identity:	127/431 - (29%)
Similarity:	205/431 - (47%)	Gaps:	70/431 - (16%)

- Green bases have known domain annotations that are detailed below.

Worm    32 ALFAYGIFVGIFVLICHIRRAFESI------NIQQYTNR----------GNAIRNSYVQVQTEIT 80
            |||..|.....|:| ..:||  |.:      .:.|:|.:          |:...:..:|:
  Fly   612 ALFLLGSAFITFML-RRLRR--EKLLKLRIETVHQWTKKVIIYRPGGEEGSGCSSGDLQM----- 668

Worm    81 PSSILAVQENTLGIEST-NKEPTQPINERAEKLPYNPAFEIQPNNLDTFNRKLGKGKFGII---- 140
            |...:..|..|:....| ..:|.|..||  .:.|.:..:|| |....:....||:|.||.:
  Fly   669 PVIRIEKQRTTVSTTGTGGTDPAQGFNE--YEFPLDSNWEI-PRQQLSLGSILGEGAFGRVVMAE 730

Worm   141 NKGLLTLRICKTNEVVQVNVAVKKMVDP-TDEKQDKLIYDEIKLMCAIGKHPNVLAIVGAITKKE 204
            .:||     .::.::.:..||||.:.:. ||.....|: .|:::|..||||.|::.::|..::..
  Fly   731 AEGL-----PRSPQLAETIVAVKMVKEEHTDTDMASLV-REMEVMKMIGKHINIINLLGCCSQGG 789

Worm   205 KVSGREYNQAVSEFIEGGDLRSVLR-NSPYTFQDEITSRERTGGQNVDAEVFDT--ISTSDLFSF 266
            .:      ..:.|:...|:|:..|: |.|...|    .|..:.|...|..:..|  :...:|..|
  Fly   790 PL------WVIVEYAPHGNLKDFLKQNRPGAPQ----RRSDSDGYLDDKPLISTQHLGEKELTKF 844

Worm   267 AYQIANGMEYLASLPCVHRDLALRNVFVKKNKIIRIGDFGLARHNGDKDYYKVKYSPETPLPIFW 331
            |:|||.|||||||..|:|||||.|||.|....:::|.||||||...|.:||:...:..  |||.|
  Fly   845 AFQIARGMEYLASRRCIHRDLAARNVLVSDGYVMKIADFGLARDIQDTEYYRKNTNGR--LPIKW 907

Worm   332 LAPECFDDGTSFTEMTDVWSYGVCLFELFSLGASPY-----LEEFQNFFDPIYYVVAFLESGKRL 391
            :|||...: ..:...:|||||||.|:|:.:.|..||     .||          :.::|.:|:|:
  Fly   908 MAPESLQE-KKYDSQSDVWSYGVLLWEIMTYGDQPYPHILSAEE----------LYSYLITGQRM 961

Worm   392 SSPKYCRSDIYNFMLECWNSDAKQRPRFTKCKEFFKNLIKR 432
            ..|..|..:||..|.:||:.::..||.|.:..|.|..::::
  Fly   962 EKPAKCSLNIYVVMRQCWHFESCARPTFAELVESFDGILQQ 1002

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
R09D1.12	NP_496025.2	TyrKc	127..426	CDD:197581	101/311 (32%)
btl	NP_001014583.1	IG_like	149..232	CDD:214653
		IGc2	157..215	CDD:197706
		IG	247..336	CDD:214652
		Ig	258..340	CDD:143165
		I-set	394..479	CDD:254352
		IGc2	408..469	CDD:197706
		IG_like	492..583	CDD:214653
		Ig	507..583	CDD:299845
		PKc_like	700..1000	CDD:304357	106/329 (32%)
		TyrKc	712..996	CDD:197581	101/312 (32%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG0200
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810