DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment chil-13 and Cht10

DIOPT Version :9

Sequence 1:	NP_496018.2	Gene:	chil-13 / 174500	WormBaseID:	WBGene00010945	Length:	439	Species:	Caenorhabditis elegans
Sequence 2:	NP_001036422.1	Gene:	Cht10 / 3355116	FlyBaseID:	FBgn0250907	Length:	2286	Species:	Drosophila melanogaster

Alignment Length:	398	Identity:	92/398 - (23%)
Similarity:	174/398 - (43%)	Gaps:	79/398 - (19%)

- Green bases have known domain annotations that are detailed below.

Worm    65 NLVLNNES--PKKPVCKRRIVGYFS---------------EIESTEISKSQIDKLTHAVFAFVRI 112
            |.||..|:  ..:...:.:|:.||:               :|:|        |..||.::.|..:
  Fly  1392 NHVLEEENIEATEMATEFKIICYFTNWAWYRQGGGKFLPEDIDS--------DLCTHIIYGFAVL 1448

Worm   113 KYDG-TLQFDNSKADL--RF--SILKDKTRGSNVEMMVSIGGGYENA-HYFASALSDSQKKKNFI 171
            ..|. |:|..:|.|||  :|  .|:..:.:|:.|  .|:|||..::| ..::..:.:.:.:..||
  Fly  1449 SRDNLTIQPHDSWADLDNKFYERIVAYRKKGAKV--TVAIGGWNDSAGDKYSRLVRNPEARSRFI 1511

Worm   172 DSILAFLVEHRIDGVDFFWQWP----------TVQDTFNYVTFIRELRQKLDENKRKHFLISMTV 226
            .::|.|:.|:..||:|..|::|          |.::...:...:|||.......       .:.:
  Fly  1512 RNVLDFIEEYNFDGLDLDWEYPVCWQVDCKKGTAEEKIGFSALVRELFYAFQPR-------GLIL 1569

Worm   227 PAAGVDNWEL---GFDLEELQNHVDFFNVYSMDYAGPWPNQWGVPTGPSSPMFYNIGARKNFYVD 288
            .||...|.::   |:::.||.::..:.:|.:.||.|    ||...||..:||:.:.....||..:
  Fly  1570 SAAVSPNKKVIDAGYEVAELSHYFSWISVMAYDYHG----QWDKKTGHVAPMYSHPEGTANFNAN 1630

Worm   289 WTMKHYTCKLKQPSMLNMVIPFSARIWNNVQEAIDNRTEVFRNAELKNNMAEGR-TQISRWTAEH 352
            ::|.::.........|.|.||...:.:     ::...|:...||........|. |:...:.|.:
  Fly  1631 FSMNYWISMGADRRKLVMGIPLYGQSF-----SLAETTKHQLNAPTYGGGEAGEATRARGFLAYY 1690

Worm   353 E-GLELSPSSWDNLTMTPYILDLKAK---------TFLTFEDKRSIKIKTDYAKKMDLGGVWLWS 407
            | .|::....|:      .:.|.|.:         .:::|:|...|:.|::|.|.|.|||..:|:
  Fly  1691 EICLKIRHHRWN------VVRDTKGRIGPFAYHGDQWVSFDDVPMIRHKSEYIKAMGLGGAMIWA 1749

Worm   408 VDMDDRLN 415
            :|:||..|
  Fly  1750 LDLDDFKN 1757

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
chil-13	NP_496018.2	Glyco_18	81..411	CDD:214753	85/374 (23%)
Cht10	NP_001036422.1	Glyco_18	220..565	CDD:214753
		GH18_chitolectin_chitotriosidase	221..586	CDD:119351
		ChtBD2	697..737	CDD:214696
		CBM_14	801..848	CDD:279884
		CBM_14	875..918	CDD:279884
		Glyco_18	966..1310	CDD:214753
		GH18_chitolectin_chitotriosidase	967..1331	CDD:119351
		Glyco_18	1410..1753	CDD:214753	85/374 (23%)
		GH18_chitolectin_chitotriosidase	1411..1774	CDD:119351	88/379 (23%)
		ChtBD2	1834..1871	CDD:214696
		Glyco_18	1909..2253	CDD:214753
		GH18_chitolectin_chitotriosidase	1910..2274	CDD:119351
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C160164222
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG3325
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D264489at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	1	1.000	-	-		mtm4747
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	6	5.750