DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Y51B9A.9 and rl

DIOPT Version :9

Sequence 1:	NP_496002.1	Gene:	Y51B9A.9 / 174489	WormBaseID:	WBGene00013091	Length:	381	Species:	Caenorhabditis elegans
Sequence 2:	NP_001015122.1	Gene:	rl / 3354888	FlyBaseID:	FBgn0003256	Length:	376	Species:	Drosophila melanogaster

Alignment Length:	335	Identity:	113/335 - (33%)
Similarity:	177/335 - (52%)	Gaps:	43/335 - (12%)

- Green bases have known domain annotations that are detailed below.

Worm     5 EILNEVLFIVPNRYVDLLPSQFGN---AMEVIAFDQISERRVVIKKVVLPENFDNWQHWRRAQRE 66
            |::...:|.|..||:.|  :..|.   .|.|.|.|.::.:||.|||:   ..|::..:.:|..||
  Fly    25 EVIRGQIFEVGPRYIKL--AYIGEGAYGMVVSADDTLTNQRVAIKKI---SPFEHQTYCQRTLRE 84

Worm    67 LFCTLHIQEENFVKMYSIYTWVETVEEMREFYTVREYMDWNLRNFILSTPEKLDHKVIKSIFFDV 131
            :......:.||.:.:..|.. |:::::||:.|.|:..|:.:|  :.|...::|.:..|....:.:
  Fly    85 ITILTRFKHENIIDIRDILR-VDSIDQMRDVYIVQCLMETDL--YKLLKTQRLSNDHICYFLYQI 146

Worm   132 CLAVQYMHSIRVGHRDLKPENVLINYEAIAKISGFAHANREDP------FVNTPYIVQRFYRAPE 190
            ...::|:||..|.||||||.|:|:|.....||..|..|...||      |: |.|:..|:|||||
  Fly   147 LRGLKYIHSANVLHRDLKPSNLLLNKTCDLKICDFGLARIADPEHDHTGFL-TEYVATRWYRAPE 210

Worm   191 ILCETMDNNKPSVDIWSLGCILAELLTGKILFTGQTQIDQFFQIVRFLGNP---DLSFYMQMPDS 252
            |:..:....| |:||||:||||||:|:.:.:|.|:..:||...|:..||:|   ||...:.  :.
  Fly   211 IMLNSKGYTK-SIDIWSVGCILAEMLSNRPIFPGKHYLDQLNHILGVLGSPSRDDLECIIN--EK 272

Worm   253 ARTFFLGLPMNQYQKPTNI--HEHFPNSLFLDTMISEPIDCDLARDLLFRMLVINPDDRIDIQKI 315
            ||.:...||.    || |:  .:.|||:           |. ||.|||.:||..||..||.:::.
  Fly   273 ARNYLESLPF----KP-NVPWAKLFPNA-----------DA-LALDLLGKMLTFNPHKRIPVEEA 320

Worm   316 LVHPYLEEVW 325
            |.|||||:.:
  Fly   321 LAHPYLEQYY 330

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Y51B9A.9	NP_496002.1	PKc_like	17..325	CDD:389743	110/321 (34%)
rl	NP_001015122.1	STKc_ERK1_2_like	32..366	CDD:270839	112/328 (34%)
rl	NP_001015122.1	S_TKc	38..326	CDD:214567	106/316 (34%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D741207at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	3	2.920