DRSC/TRiP Functional Genomics Resources

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Protein Alignment mpk-2 and rl

DIOPT Version :9

Sequence 1:NP_494946.2 Gene:mpk-2 / 173880 WormBaseID:WBGene00003402 Length:605 Species:Caenorhabditis elegans
Sequence 2:NP_001015122.1 Gene:rl / 3354888 FlyBaseID:FBgn0003256 Length:376 Species:Drosophila melanogaster


Alignment Length:382 Identity:150/382 - (39%)
Similarity:224/382 - (58%) Gaps:15/382 - (3%)


- Green bases have known domain annotations that are detailed below.


 Worm    24 YSISKNTVNKSKMAAPAESHAR-LDGRFWLEGTPYLAEENVGAGAYGVVCKAMDTRNKKQVAIKK 87
            ::.|.:.||.:......:|:|. :.|:.:..|..|:....:|.||||:|..|.||...::|||||
  Fly     4 FNSSGSVVNGTGSTEVPQSNAEVIRGQIFEVGPRYIKLAYIGEGAYGMVVSADDTLTNQRVAIKK 68

 Worm    88 IPRAFTAHTLAKRSLREVRILRELLHENIIAVLDMFTAEGA-HGKDIYLVMDLMETDLHQILHSR 151
            | ..|...|..:|:|||:.||....|||||.:.|:...:.. ..:|:|:|..||||||:::|.: 
  Fly    69 I-SPFEHQTYCQRTLREITILTRFKHENIIDIRDILRVDSIDQMRDVYIVQCLMETDLYKLLKT- 131

 Worm   152 QTLMEQHFQYFFYQLLRGLKYLHSAGIIHRDLKPSNLLLNGDCLLRIADFGMARAYASASTVRDD 216
            |.|...|..||.||:||||||:|||.::||||||||||||..|.|:|.|||:||.   |....|.
  Fly   132 QRLSNDHICYFLYQILRGLKYIHSANVLHRDLKPSNLLLNKTCDLKICDFGLARI---ADPEHDH 193

 Worm   217 ANVGGHMTQYVSTRWYRAPEILFSMVEYDTKVDLWSAGCIFAEMLLRRQLFPGKDSVSQIKMIVY 281
            .   |.:|:||:|||||||||:.:...|...:|:||.|||.||||..|.:||||..:.|:..|:.
  Fly   194 T---GFLTEYVATRWYRAPEIMLNSKGYTKSIDIWSVGCILAEMLSNRPIFPGKHYLDQLNHILG 255

 Worm   282 YLGSPEEEVINRITSDLVRDSIEACGRKTPLPFSAIFPKASPEARNMVSYLLQISPWKRYSADQI 346
            .||||..:.:..|.::..|:.:|:...|..:|::.:||.|...|.:::..:|..:|.||...::.
  Fly   256 VLGSPSRDDLECIINEKARNYLESLPFKPNVPWAKLFPNADALALDLLGKMLTFNPHKRIPVEEA 320

 Worm   347 LQHPFMAQYHNDQYEPLC--PPRVQVDVDAIERFEGAQVVAGLDEEARIFEMRRGTN 401
            |.||::.||::...||:.  |.|:.::.|.|.|.....::.   ||...|:.|:..|
  Fly   321 LAHPYLEQYYDPGDEPVAEVPFRINMENDDISRDALKSLIF---EETLKFKERQPDN 374

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
mpk-2NP_494946.2 PKc_like 54..376 CDD:304357 137/324 (42%)
S_TKc 57..352 CDD:214567 129/295 (44%)
rlNP_001015122.1 STKc_ERK1_2_like 32..366 CDD:270839 141/344 (41%)
S_TKc 38..326 CDD:214567 129/295 (44%)


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 1 1.010 - - D309855at33208
OrthoFinder 1 1.000 - - FOG0000164
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 1 0.900 - - OOG6_100339
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
43.820

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