DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment chil-24 and Cht10

DIOPT Version :9

Sequence 1:	NP_494455.1	Gene:	chil-24 / 173661	WormBaseID:	WBGene00020407	Length:	410	Species:	Caenorhabditis elegans
Sequence 2:	NP_001036422.1	Gene:	Cht10 / 3355116	FlyBaseID:	FBgn0250907	Length:	2286	Species:	Drosophila melanogaster

Alignment Length:	416	Identity:	88/416 - (21%)
Similarity:	168/416 - (40%)	Gaps:	93/416 - (22%)

- Green bases have known domain annotations that are detailed below.

Worm    23 VCRHCHEKQDSTFFSIHSNYKMSNNETETTPS----RIVGFYADWE----------RTDITSHQV 73
            |.:.|..:.:.....:..|:.:.....|.|..    :|:.::.:|.          ..||.|.
  Fly  1374 VMQTCENEGEEHEGILDPNHVLEEENIEATEMATEFKIICYFTNWAWYRQGGGKFLPEDIDSD-- 1436

Worm    74 AKLTHAVFAYVQMKFDGSLGFKNDAARIRFSNLRDKVRRNEDSNVKMMISIGGFENS--QHFYPV 136
             ..||.::.:..:..|......:|:.....:...:::........|:.::|||:.:|  ..:..:
  Fly  1437 -LCTHIIYGFAVLSRDNLTIQPHDSWADLDNKFYERIVAYRKKGAKVTVAIGGWNDSAGDKYSRL 1500

Worm   137 LSNVEMKKAFLNSISSFLAYHELHGVDIFWKWP----------SPEDKAHYSRFLADLRQHLGYE 191
            :.|.|.:..|:.::..|:..:...|:|:.|::|          :.|:|..:|.    |.:.|.|.
  Fly  1501 VRNPEARSRFIRNVLDFIEEYNFDGLDLDWEYPVCWQVDCKKGTAEEKIGFSA----LVRELFYA 1561

Worm   192 F-----IISVAV-PQAEVSNLELGYDLRTISSHVDFFNVHSMDYYGPWPNEWGKPTGPISPLY-- 248
            |     |:|.|| |..:|  ::.||::..:|.:..:.:|.:.||:|    :|.|.||.::|:|
  Fly  1562 FQPRGLILSAAVSPNKKV--IDAGYEVAELSHYFSWISVMAYDYHG----QWDKKTGHVAPMYSH 1620

Worm   249 --GPTRHNVDWTLRYYAEKTGEPGKLNMVIPFFVRLWKNVPEPVEPGRQVFRDVELVD---NKP- 307
              |....|.::::.|:.....:..||.|.||.:              .|.|...|...   |.|
  Fly  1621 PEGTANFNANFSMNYWISMGADRRKLVMGIPLY--------------GQSFSLAETTKHQLNAPT 1671

Worm   308 -----QGEAYMSRWSAQHEELDLSPADWDEETRSSYTWN--PDTR-----------NFVTFETDK 354
                 .|||..:|....:.|:.|.        ...:.||  .||:           .:|:|:...
  Fly  1672 YGGGEAGEATRARGFLAYYEICLK--------IRHHRWNVVRDTKGRIGPFAYHGDQWVSFDDVP 1728

Worm   355 SIQEKMKYVKEKNLGGVWIWHVDANE 380
            .|:.|.:|:|...|||..||.:|.::
  Fly  1729 MIRHKSEYIKAMGLGGAMIWALDLDD 1754

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
chil-24	NP_494455.1	Glyco_18	55..378	CDD:214753	82/376 (22%)
Cht10	NP_001036422.1	Glyco_18	220..565	CDD:214753
		GH18_chitolectin_chitotriosidase	221..586	CDD:119351
		ChtBD2	697..737	CDD:214696
		CBM_14	801..848	CDD:279884
		CBM_14	875..918	CDD:279884
		Glyco_18	966..1310	CDD:214753
		GH18_chitolectin_chitotriosidase	967..1331	CDD:119351
		Glyco_18	1410..1753	CDD:214753	83/377 (22%)
		GH18_chitolectin_chitotriosidase	1411..1774	CDD:119351	83/379 (22%)
		ChtBD2	1834..1871	CDD:214696
		Glyco_18	1909..2253	CDD:214753
		GH18_chitolectin_chitotriosidase	1910..2274	CDD:119351
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C160164212
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG3325
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	1	1.000	-	-		mtm4747
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	4	3.740