| Sequence 1: | NP_001106669.1 | Gene: | Mitf / 17342 | MGIID: | 104554 | Length: | 526 | Species: | Mus musculus |
|---|---|---|---|---|---|---|---|---|---|
| Sequence 2: | NP_001245436.1 | Gene: | Mitf / 3885647 | FlyBaseID: | FBgn0263112 | Length: | 837 | Species: | Drosophila melanogaster |
| Alignment Length: | 624 | Identity: | 179/624 - (28%) |
|---|---|---|---|
| Similarity: | 250/624 - (40%) | Gaps: | 225/624 - (36%) |
- Green bases have known domain annotations that are detailed below.
|
Mouse 37 SAEHSGASKPPLS------SSTMTSRILLRQQLMREQMQEQERREQQQKL--------------- 80
Mouse 81 -------------------------QAAQFMQQRVAVSQTPAINVSVPTTLPS-ATQVPMEVLKV 119
Mouse 120 QTHLENPTKYHIQQAQRHQVKQYLSTT--------------LANKHAS----------QVLSSP- 159
Mouse 160 -------CPN-------QPGDHAMPPVP------------------------------------- 173
Mouse 174 -GSSAPNSPMAMLTLNS---NCEKEAFYKFEEQSRAESECPGMNTHSRASCMQMDDVIDDII--- 231
Mouse 232 --SLESSYNEEILGLMDPALQMANTLPVSGNLIDLYSNQGLPPPGLTISNSCPANLPNIKRELTA 294
Mouse 295 CIFPTESEARALAKERQKKDNHNLIERRRRFNINDRIKELGTLIPKSNDP------DMRWNKGTI 353
Mouse 354 LKASVDYIRKLQREQQRAKDLENRQKKLEHANRHLLLRVQELEMQARAHGLSLIPS--TGLCSPD 416
Mouse 417 LVNRIIKQEPVLENCSQELVQHQA-----DLTCTTTLDLTDGTITFTNNLGTMPESSPAYSIPRK 476
Mouse 477 MGSNLEDILMDDALSPVGVTDPLLSSVSPGASKTSSRRS 515 |
| Gene | Sequence | Domain | Region | External ID | Identity |
|---|---|---|---|---|---|
| Mitf | NP_001106669.1 | Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite | 20..54 | 7/22 (32%) | |
| MITF_TFEB_C_3_N | 56..194 | CDD:406384 | 59/258 (23%) | ||
| Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite | 155..179 | 10/76 (13%) | |||
| Transactivation. /evidence=ECO:0000250 | 224..291 | 12/71 (17%) | |||
| bHLHzip_MITF | 300..403 | CDD:381496 | 66/108 (61%) | ||
| Leucine-zipper. /evidence=ECO:0000305|PubMed:23207919 | 374..395 | 8/20 (40%) | |||
| DUF3371 | 397..522 | CDD:403149 | 31/126 (25%) | ||
| DNA binding regulation. /evidence=ECO:0000250 | 401..431 | 8/31 (26%) | |||
| Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite | 496..526 | 9/20 (45%) | |||
| Mitf | NP_001245436.1 | MITF_TFEB_C_3_N | <272..>311 | CDD:292573 | 14/94 (15%) |
| HLH | 505..570 | CDD:238036 | 18/71 (25%) |
| Tool | Simple Score | Weighted Score | Original Tool Information | |||
|---|---|---|---|---|---|---|
| BLAST Result | Score | Score Type | Cluster ID | |||
| Compara | 1 | 0.930 | - | - | C167847996 | |
| Domainoid | 1 | 1.000 | 85 | 1.000 | Domainoid score | I8160 |
| eggNOG | 1 | 0.900 | - | - | E1_KOG1318 | |
| Hieranoid | 0 | 0.000 | Not matched by this tool. | |||
| Homologene | 0 | 0.000 | Not matched by this tool. | |||
| Inparanoid | 1 | 1.050 | 144 | 1.000 | Inparanoid score | I4416 |
| Isobase | 0 | 0.000 | Not matched by this tool. | |||
| OMA | 0 | 0.000 | Not matched by this tool. | |||
| OrthoDB | 1 | 1.010 | - | - | D1211990at2759 | |
| OrthoFinder | 1 | 1.000 | - | - | FOG0000691 | |
| OrthoInspector | 1 | 1.000 | - | - | otm43034 | |
| orthoMCL | 1 | 0.900 | - | - | OOG6_109347 | |
| Panther | 1 | 1.100 | - | - | LDO | PTHR45776 |
| Phylome | 1 | 0.910 | - | - | ||
| RoundUp | 1 | 1.030 | - | avgDist | Average_Evolutionary_Distance | R1708 |
| SonicParanoid | 1 | 1.000 | - | - | X566 | |
| SwiftOrtho | 0 | 0.000 | Not matched by this tool. | |||
| TreeFam | 1 | 0.960 | - | - | ||
| 13 | 12.790 | |||||