Protein Alignment gadr-6 and CG12084

DIOPT Version :9

• Sequence 1: NP_493455.1
• Gene: gadr-6 / 173273
• WormBaseID: WBGene00009823
• Length: 710
• Species: Caenorhabditis elegans
• Sequence 2: NP_612112.1
• Gene: CG12084 / 192509
• FlyBaseID: FBgn0043458
• Length: 793
• Species: Drosophila melanogaster
• Alignment Length: 673
• Identity: 134/673 - (19%)
• Similarity: 233/673 - (34%)
• Gaps: 209/673 - (31%)

 Worm   106 RLFRTSQIDHLDLSGRSQFSTAWLKTTGQQ-----LPLLRTLNVSGVKLLNPDFF---QFCKSFP 162
            ||.....:|...|:         ||....|     |.::.:....|.:.|||...   :.|..|.
  Fly     6 RLMEDGSLDEEPLT---------LKEIAYQKLCNNLDIISSHRPDGQRGLNPGIVLPNEICDGFL 61

 Worm   163 NLYS-----LDISNCGVTILTGISRLK--NLRHLSLRSLIYESWYDIRELFALKL-----LNV-- 213
            ..|.     ||.|...:...|..:.||  |||:.:|.|:..|:... .:||||.|     ::|
  Fly    62 ENYQRFNRPLDDSVIRLFEDTHRTSLKIVNLRNSTLSSIGLETLMR-HKLFALSLWYCDMISVGS 125

 Worm   214 ---------------LDLSMHSTHHARRNMQRFLDCKQVLPELRFLECSGNLMDEDMLEELLITH 263
                           |.:|.|...:|..|.:..:|.:...|.||.|..:|.:|..      .:..
  Fly   126 HHLLAHYGDSLRSLELGISSHLLQYAEPNEKEPVDFQLTCPHLRRLVLNGVVMHH------RLQF 184

 Worm   264 SHLHQLAIVDCDVKAPKSSPIRILSCTTFDSSITALKYYLNLKRRNEVQICFQELRLHVKRLHER 328
            :|||.|..:|            :.||...:.|:.||....||    ...|.|....: ..:||
  Fly   185 AHLHDLGHLD------------LTSCVLANFSLEALGSLPNL----HTLILFNVWPI-ANQLH-- 230

 Worm   329 KMQYDVTECVTLSLQSLEKLPCSLIMN----------FDIVEERLFTSRLSFEADFLAEIVLHNF 383
                        ::..|.:| |:|.::          :|:.::.|             |:::.|.
  Fly   231 ------------AICCLRRL-CTLDISISSSGNGHGTYDLPDQTL-------------EMLMDNL 269

 Worm   384 HRLSRVHTRLICDILLNNVNRQLIRDLRAETMWNAIIYLFNMGVFVDKQKLKGIAS--------- 439
            ..|:.:      ||...|:....:. .:..|..:.:.....|........:.|:||
  Fly   270 RHLTHL------DISGTNLAGNGVA-TKESTTTSGMQQSPKMEQHFALTDIPGLASRTQRPLQFL 327

 Worm   440 ------HCAASLHNGDPIIEEQAMRILTSCVTGKTLE-LVLSITESKHDTTPICLGFLRAALHKE 497
                  |.|...|: .|.:|          |.|...| .:|:.....|| .|:.|
  Fly   328 GLYHTAHWACKRHD-IPALE----------VAGDANEQQILTAARYYHD-RPVLL---------- 370

 Worm   498 DEQSSRRVAEKILAATHN--NEEECKRYIKHGAMNMLISAIDRFDSEPMHIVILGIIRNLVMMSP 560
                     .::|...::  ..|.||..  |.|:::::||:|| ..:..|:.|.|......::..
  Fly   371 ---------TRVLNDLYHLFRFENCKDI--HTALDVVLSAMDR-HLKFKHMQISGSATLFYIVKG 423

 Worm   561 YDKVQQIFTCVQFRTFQILLRNWTSSDRAYLMLSIFALRLNHQDKNFECVFRKCADELLRKHFPY 625
            .|:.:          |..||||           .|....||..:.:.      ..|.:||.  .|
  Fly   424 RDRSK----------FGALLRN-----------HIIRTLLNGMEMHI------TDDTMLRN--GY 459

 Worm   626 LLATEITVDVDIYFD-----RGIVQNILRTSEE-----VGLVLWALLTIKIYAQKSLWNSRSIRD 680
            |..|:..:.||:.|:     :.::..:.:|.:|     :.:.|...|..::..::.|:.......
  Fly   460 LTLTQFHMPVDVLFEYERLIKILLHGVSKTEQEGFVQRIAIYLLNTLACQVDGRQKLFLGELGVV 524

 Worm   681 SNFFYLIEN---PHIASEVVNVA 700
            |..|.||::   ..:..:|:.||
  Fly   525 STMFTLIKDRLTRSVFDDVMEVA 547

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
gadr-6	NP_493455.1	leucine-rich repeat	86..112	CDD:275381	2/5 (40%)
		leucine-rich repeat	113..138	CDD:275381	6/29 (21%)
		leucine-rich repeat	139..163	CDD:275381	6/26 (23%)
		leucine-rich repeat	164..185	CDD:275381	7/27 (26%)
CG12084	NP_612112.1	leucine-rich repeat	110..135	CDD:275381	6/24 (25%)
		leucine-rich repeat	136..167	CDD:275381	6/30 (20%)
		leucine-rich repeat	168..189	CDD:275381	7/26 (27%)
		leucine-rich repeat	190..213	CDD:275381	7/34 (21%)
		ARM	535..628	CDD:237987	3/13 (23%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3665
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810