DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Mesp1 and Fer3

DIOPT Version :9

Sequence 1:	NP_032614.2	Gene:	Mesp1 / 17292	MGIID:	107785	Length:	243	Species:	Mus musculus
Sequence 2:	NP_524322.1	Gene:	Fer3 / 41411	FlyBaseID:	FBgn0037937	Length:	195	Species:	Drosophila melanogaster

Alignment Length:	165	Identity:	50/165 - (30%)
Similarity:	68/165 - (41%)	Gaps:	47/165 - (28%)

- Green bases have known domain annotations that are detailed below.

Mouse    21 QPPMPSDGNSVCSPAWSSD----PWDGAQASSPAPPCARPARR--AG-----------------T 62
            |.|.|.|     .|.:..|    |..|.:|  |.||.. |.:.  ||                 .
  Fly     2 QHPHPID-----QPTYMPDVPFQPLWGQEA--PPPPIV-PYQELIAGFPCTDLSLWQRSQVTPLV 58

Mouse    63 PGRRGTHGSRLGS--------------GQRQSASEREKLRMRTLARALHELRRFLPPSVAPTGQN 113
            |.|..|:|...||              .||::|:.||:.||..|..|..:|||.:|.....  :.
  Fly    59 PQRPSTNGRANGSSSSSKKTRRRVASMAQRRAANIRERRRMFNLNEAFDKLRRKVPTFAYE--KR 121

Mouse   114 LTKIETLRLAIRYIGHLSAVLGLSEDNLRRQRHAV 148
            |::||||||||.|||.::.:|..:..|..:.|..|
  Fly   122 LSRIETLRLAITYIGFMAELLSGTPSNSHKSRSDV 156

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Mesp1	NP_032614.2	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	1..86		25/101 (25%)
		HLH	77..130	CDD:278439	25/52 (48%)
		CPLCP	153..157
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	204..228
Fer3	NP_524322.1	HLH	87..135	CDD:278439	22/49 (45%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG4029
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810