DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Meox2 and Antp

DIOPT Version :9

Sequence 1:	NP_032610.1	Gene:	Meox2 / 17286	MGIID:	103219	Length:	303	Species:	Mus musculus
Sequence 2:	NP_996167.1	Gene:	Antp / 40835	FlyBaseID:	FBgn0260642	Length:	378	Species:	Drosophila melanogaster

Alignment Length:	280	Identity:	77/280 - (27%)
Similarity:	106/280 - (37%)	Gaps:	81/280 - (28%)

- Green bases have known domain annotations that are detailed below.

Mouse    12 PHATAQGLHPFSQ-------SSLALHGRSDHMS-YPELSTSSSSCIIAGYPNEEGMFASQHHRGH 68
            |..|.|..||..|       :|..|......:. .||..:......::|: :........||.||
  Fly   140 PQVTQQVTHPQQQQQQPVVYASCKLQAAVGGLGMVPEGGSPPLVDQMSGH-HMNAQMTLPHHMGH 203

Mouse    69 H-----------------HHHHHHHHHHQQQQHQALQSNWHLPQMSSPPSAARHSLCLQPDSGGP 116
            .                 |.:||:...:|||.        .:|.:.:||....|      ...||
  Fly   204 PQAQLGYTDVGVPDVTEVHQNHHNMGMYQQQS--------GVPPVGAPPQGMMH------QGQGP 254

Mouse   117 PELGS------SPPVLCSNSSSLGSSTPTGAACAPGDYGRQALSPADVEKRSGSKRKSDSSDSQE 175
            |::..      :||....||.|.|..:|              |.|         ..:|.....||
  Fly   255 PQMHQGHPGQHTPPSQNPNSQSSGMPSP--------------LYP---------WMRSQFGKCQE 296

Mouse   176 GNYKSEVNSKPRKERTAFTKEQIRELEAEFAHHNYLTRLRRYEIAVNLDLTERQVKVWFQNRRMK 240
                      .::.|..:|:.|..|||.||..:.||||.||.|||..|.|||||:|:||||||||
  Fly   297 ----------RKRGRQTYTRYQTLELEKEFHFNRYLTRRRRIEIAHALCLTERQIKIWFQNRRMK 351

Mouse   241 WKRVK--GGQQGAAAREKEL 258
            ||:..  .|:.|:.....|:
  Fly   352 WKKENKTKGEPGSGGEGDEI 371

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Meox2	NP_032610.1	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	63..191		29/150 (19%)
		Homeobox	190..242	CDD:278475	32/51 (63%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	278..303
Antp	NP_996167.1	KLF1_2_4_N	<161..306	CDD:425360	35/192 (18%)
Antp	NP_996167.1	Homeobox	301..354	CDD:395001	33/52 (63%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG0489
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X14
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.810