Protein Alignment CYB5R3 and CG5946

DIOPT Version :10

• Sequence 1: NP_001165131.1
• Gene: CYB5R3 / 1727
• HGNCID: 2873
• Length: 334
• Species: Homo sapiens
• Sequence 2: NP_001287035.1
• Gene: CG5946 / 39336
• FlyBaseID: FBgn0036211
• Length: 330
• Species: Drosophila melanogaster
• Alignment Length: 282
• Identity: 164/282 - (58%)
• Similarity: 205/282 - (72%)
• Gaps: 15/282 - (5%)

Human    68 TLESPDIKYPLRLIDREIISHDTRRFRFALPSPQHILGLPVGQHIYLSARIDGNLVVRPYTPISS 132
            ||..|:.||.|.||::|.:|||||||||.|||.||:|||||||||:|.|.||..|::||||||||
  Fly    49 TLVDPNDKYLLPLIEKENLSHDTRRFRFGLPSKQHVLGLPVGQHIHLIATIDNELIIRPYTPISS 113

Human   133 DDDKGFVDLVIKVYFKDTHPKFPAGGKMSQYLESMQIGDTIEFRGPSGLLVYQGKGKFAIRPDKK 197
            |:|.|:||||:||||||:||||||||||:|:||.:::||.|.||||||.|.|.|.|.|:|:..:|
  Fly   114 DEDVGYVDLVVKVYFKDSHPKFPAGGKMTQHLEQLELGDKISFRGPSGRLQYLGNGTFSIKKLRK 178

Human   198 SNPIIRTVKSVGMIAGGTGITPMLQVIRAIMKDPD-DHTVCHLLFANQTEKDILLRPELEELRNK 261
            ..|...|.|.|.|||||||||||||:.|.::|..| |.|...||||||:|||||||.||:||..|
  Fly   179 DPPKHVTAKRVNMIAGGTGITPMLQLAREVLKRSDKDKTELALLFANQSEKDILLRAELDELAQK 243

Human   262 HSARFKLWYTLDRAPE--------------AWDYGQGFVNEEMIRDHLPPPEEEPLVLMCGPPPM 312
            |..:||:|||:|:|.|              ||.|..|.||::|::.||.||.|:.|.|:||||||
  Fly   244 HPDQFKIWYTVDKANEAIKRMPRMGNARFVAWSYNTGHVNDDMMQQHLYPPGEDTLCLLCGPPPM 308

Human   313 IQYACLPNLDHVGHPTERCFVF 334
            :.|.|:|.|:.:||..|:.|.:
  Fly   309 VNYTCIPGLERLGHRAEQRFSY 330

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CYB5R3	NP_001165131.1	PLN02252	<71..334	CDD:215141	162/277 (58%)
CG5946	NP_001287035.1	PLN02252	<50..330	CDD:215141	163/279 (58%)