DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment nuo-2 and ND-30

DIOPT Version :9

Sequence 1:	NP_871796.1	Gene:	nuo-2 / 172363	WormBaseID:	WBGene00020417	Length:	268	Species:	Caenorhabditis elegans
Sequence 2:	NP_647775.1	Gene:	ND-30 / 38378	FlyBaseID:	FBgn0266582	Length:	265	Species:	Drosophila melanogaster

Alignment Length:	256	Identity:	155/256 - (60%)
Similarity:	188/256 - (73%)	Gaps:	9/256 - (3%)

- Green bases have known domain annotations that are detailed below.

Worm     9 AVSRQIVRNSPISTTAAVAQTNQTGDKKESPKKPTIWKIDEHKRERLANFGKYAAECLPKFVQKV 73
            |:|.:.|..:..||...:|.|.....||..  |||:.:.|...|..|::||:|.||||||:||||
  Fly    16 ALSAKHVVPAAGSTALRMASTTPVEPKKAD--KPTVRQPDAVARSHLSDFGRYVAECLPKYVQKV 78

Worm    74 QFAAGDELELLIHPSGVVPVLSFLKGNHSAQFTNLTFITGMDVPTRKNRLEVIYSLYSVRFNARV 138
            |..||||||:||.|.||||||.|||.:|.||||||..|.|:|||.||||.||:|:|.|:|:|:|:
  Fly    79 QLTAGDELEVLIAPEGVVPVLQFLKDHHQAQFTNLVDIAGVDVPCRKNRFEVVYNLLSLRYNSRI 143

Worm   139 RVRTYTDEIAPIDSATPVFKGADWFEREVYDMYGVWFNNHPDLRRILTDYGFEGHPFRKDYPLSG 203
            ||:|||||:.|:|||..|.|.|:|:|||::|||||:|.||||||||||||||||||.|:|:||||
  Fly   144 RVKTYTDELTPLDSACEVHKAANWYEREIWDMYGVFFANHPDLRRILTDYGFEGHPQRRDFPLSG 208

Worm   204 YNEVRYDPELKRVVYEPSELAQEFRKFDLNTPWETFPAFRNQSITSGYETILEVAEP-TPA 263
            |.|:|||.|.||||.||.|||||||||||:.|||.||.|||.:..:      ||..| .||
  Fly   209 YVELRYDDEKKRVVCEPLELAQEFRKFDLSAPWEQFPNFRNANPPA------EVVPPQAPA 263

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
nuo-2	NP_871796.1	PRK06074	53..237	CDD:235691	129/183 (70%)
ND-30	NP_647775.1	PRK06074	60..242	CDD:235691	129/181 (71%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C160167636
Domainoid	1	1.000	188	1.000	Domainoid score	I1963
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H3346
Inparanoid	1	1.050	306	1.000	Inparanoid score	I1587
Isobase	1	0.950	-	0.906565	Normalized mean entropy	S2902
OMA	1	1.010	-	-		QHG51846
OrthoDB	1	1.010	-	-		D1276923at2759
OrthoFinder	1	1.000	-	-		FOG0005716
OrthoInspector	1	1.000	-	-		oto19403
orthoMCL	1	0.900	-	-		OOG6_101398
Panther	1	1.100	-	-	LDO	PTHR10884
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R3435
SonicParanoid	1	1.000	-	-		X4118
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	16	15.890