DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment bet-1 and tbrd-3

DIOPT Version :9

Sequence 1:	NP_001366626.1	Gene:	bet-1 / 172054	WormBaseID:	WBGene00022473	Length:	857	Species:	Caenorhabditis elegans
Sequence 2:	NP_726307.1	Gene:	tbrd-3 / 246604	FlyBaseID:	FBgn0050417	Length:	268	Species:	Drosophila melanogaster

Alignment Length:	246	Identity:	60/246 - (24%)
Similarity:	104/246 - (42%)	Gaps:	57/246 - (23%)

- Green bases have known domain annotations that are detailed below.

Worm   261 PSMKPCLKLLNDFSTKKYQEFAWPFNEPVDAEQLGLHDYHKIIKEPMDLKSMKAKMESGAYKEPS 325
            |.:..|..::....:..|:..||.|.||:|.:.|||||||:|::|||||.:::.::.:|.|...:
  Fly    12 PEINACKVIIKRLFSSTYKNIAWVFYEPLDPQLLGLHDYHEIVREPMDLSTVRHRLNTGCYLSAA 76

Worm   326 DFEHDVRLMLRNCFLYNPVGDPVHSFGLRFQEVFDRRWAEL---------------------GDS 369
            ||..|:||:..|.:||.......:....:.|.:|:..::::                     .||
  Fly    77 DFAKDIRLIFYNTYLYTNPDHLCYHMAKQLQIIFEEMYSQVQLYICSSGSKVRAEEESSSDESDS 141

Worm   370 SS-----RASSVAP--QSAP--------IAPT-----PKVAKSSAPKEP---KESRKEHKKETTF 411
            ||     ..|.|:|  ..||        ..||     |...::|..:||   :|....|.|....
  Fly   142 SSPEDEVNGSEVSPSIMGAPPSCTPTTECTPTPDWTPPATLETSEQQEPFTTEEDLDLHAKIQQL 206

Worm   412 EASGAKSEDLMQINNALSMIRERE--------EKLKAELAAAQAIKDKLTS 454
            :     .|.|:.:.:.:..:...|        :..|.::...:.|:|.|.|
  Fly   207 D-----GEVLLHVIHFIQRMEGAEYCNKELEFDICKLKVHTKRGIRDYLAS 252

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
bet-1	NP_001366626.1	Bromo_Brdt_I_like	39..145	CDD:99929
		PLN02967	95..>240	CDD:215521
		Bromo_Brdt_II_like	262..363	CDD:99930	33/100 (33%)
		Ribosomal_P1_P2_L12p	<371..416	CDD:419700	15/67 (22%)
		BET	526..592	CDD:407211
		DMRT-like	<684..730	CDD:374115
tbrd-3	NP_726307.1	Bromo_Brdt_II_like	13..114	CDD:99930	33/100 (33%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000322
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR22880
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X197
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	4	4.010