Protein Alignment rnf-145 and rnf145b

DIOPT Version :9

• Sequence 1: NP_491382.2
• Gene: rnf-145 / 172053
• WormBaseID: WBGene00022471
• Length: 742
• Species: Caenorhabditis elegans
• Sequence 2: NP_956057.1
• Gene: rnf145b / 327056
• ZFINID: ZDB-GENE-030131-5264
• Length: 685
• Species: Danio rerio
• Alignment Length: 688
• Identity: 203/688 - (29%)
• Similarity: 350/688 - (50%)
• Gaps: 57/688 - (8%)

 Worm    51 VLETGLRLPGLLFIELLWRYQGFS-FEDISDDMMKQTPLSYFDIPTMLDFVHRRNFDHHAAIILS 114
            ||..|||:|.::.:|:|:|:...| |:.|....:...|:..:               .:.|:.|.
Zfish    10 VLNVGLRIPSIMLLEVLYRWDVSSFFQKIQRSSLNNNPVFQY---------------KYIALYLH 59

 Worm   115 YFVIFISLMFLTLPLSRLIRMYSHFLSVFLFGVAYKLSAIYVDLEMKTG-EEELKLDGLIKLERH 178
            |....:||:.||||...|:::|.:.|:..|....::||..||..|:.:| |..|.|:.| .:.|.
Zfish    60 YVGYILSLVLLTLPRQHLVQLYLYVLTALLLFAGHQLSRDYVRGELDSGYEGPLYLEPL-SMNRF 123

 Worm   179 GFHFLAQMLLVVLQSMLLEVDGEPWRVALPVFALPIVARMCGCPMDKLKNAHNYACTGTMIFIAT 243
            ....:.|:::..|.|.:::. .:.|  ......||:|||:|..|::.:...:.:|    |||...
Zfish   124 TTALIGQVVVCTLCSCVMQT-RQIW--LFSAHLLPLVARLCLVPLETIVFINRFA----MIFTGL 181

 Worm   244 YMLYRAPSLI----KSTKTALRQIKAVFMVHG-LADGVAVLWRKLRILELLTFTWITMFLMVLYV 303
            .:||...|.:    ...|||.|::..|..|:| ||.|:: ||.:|.:..|....|:.:|.:.:|.
Zfish   182 EVLYFIASNLLVPYNLAKTAYRELVQVVEVYGLLALGMS-LWNQLVLPVLFMCFWLVLFALQIYT 245

 Worm   304 ELIDKGRTWSEVGRIL---LTGVAETTNTPITLAALAVSVSYVCKWIADLTKLITGGTRSHGHVL 365
            ....:.:..|. .|:|   ||.:||..:||.:|..|..:||:|...:..|.|....|.|:..:..
Zfish   246 YFSTRDQPPSR-ERLLFLFLTSIAECCSTPYSLLGLVFTVSFVALGVLTLCKFYLQGYRAFMNDN 309

 Worm   366 A-HSGYTEAVSVVILCIQTGFLGMQVEQKTILLALVLYIVISALLQSLFEIIEVVLLNLPSSPTA 429
            | |.|.||.::::||.:|||.:.:||..:..||:::|:||::::|||:.||.:.::|.|.:|...
Zfish   310 AMHRGMTEGITLLILAVQTGLIELQVIHRAFLLSIILFIVVASILQSMLEIADPIVLALGASRDK 374

 Worm   430 SRARHARCICIALLLVVIPFFTTKTMLALLPIDIYTAIIIANSATVTARAIGVILKYIVLIVETK 494
            |..:|.|.:.:.|.|:|.|.:....:.....:|.:..|||::|...:.:.:|.:|.|::.:||..
Zfish   375 SLWKHFRAVSLCLFLLVFPAYMAYMICQFFRMDFWLLIIISSSILTSLQVLGTLLIYVLFMVEEF 439

 Worm   495 SEEPWEGIDDLTYYIDCANKGIELLAAKVVMVFGCMQVVKVGFSFATFAILLFHVIVNIYKRLE- 558
            .:.|.|.:|::.||::...:.:|.|.|..|:.:|..:.:...::.....|:|.|...|::.|.:
Zfish   440 RKAPVENMDEVIYYVNGTYRLLEFLVAVCVVAYGVSETLFGEWTVMGSTIILVHSYYNVWLRAQL 504

 Worm   559 HTVSFIKNRNAAVKNINRLSKADVVQLREREDVCAICFIEMKEEARITPCKHYFHGPCLRKWLAV 623
            ...||:..|: ||..|..:..|..:||::..|:|:|||.:|| .|.||||.|:||..||:|||.|
Zfish   505 GWQSFLLRRD-AVHKIQSMPTASTLQLQQHNDICSICFQDMK-SAVITPCSHFFHAACLKKWLYV 567

 Worm   624 KMVCPLCYTYMKEDDFDSKSSSSGTLNEVQQNEEGAAVEENPENPEEQPEAPNAERAPGDMFDWD 688
            :..||||:..:|..  ...:||.||     ..:...|..:||...|::...|..|....:
Zfish   568 QETCPLCHGQLKSQ--LQPTSSPGT-----PTQGTPAANQNPREVEQEQRQPQVELNTEE----- 620

 Worm   689 DLFGFRAERETRNRNEQRIHGARDMWPLLVDNDAYESD 726
               |.||| |.:...||::  ..|:.|..::....|.|
Zfish   621 ---GIRAE-EMKTSAEQKL--GMDLLPGSLNTQPKECD 652

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
rnf-145	NP_491382.2	TRC8_N	49..556	CDD:372682	146/515 (28%)
		RING-H2_RNF139_like	590..631	CDD:319390	24/40 (60%)
rnf145b	NP_956057.1	TRC8_N	8..506	CDD:290425	147/520 (28%)
		zf-RING_2	535..575	CDD:290367	24/40 (60%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	582..685		21/87 (24%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	207	1.000	Domainoid score	I1833
eggNOG	1	0.900	-	-		E1_COG5243
Hieranoid	0	0.000	Not matched by this tool.
Homologene	1	1.000	-	-		H137692
Inparanoid	1	1.050	279	1.000	Inparanoid score	I2008
OMA	1	1.010	-	-		QHG46488
OrthoDB	1	1.010	-	-		D302551at33208
OrthoFinder	1	1.000	-	-		FOG0006288
OrthoInspector	1	1.000	-	-		otm12138
orthoMCL	1	0.900	-	-		OOG6_109881
Panther	1	1.100	-	-	O	PTHR22763
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X4575
SwiftOrtho	1	1.000	-	-
TreeFam	1	0.960	-	-
	14	13.840