Protein Alignment rnf-145 and Rnf145

DIOPT Version :9

• Sequence 1: NP_491382.2
• Gene: rnf-145 / 172053
• WormBaseID: WBGene00022471
• Length: 742
• Species: Caenorhabditis elegans
• Sequence 2: NP_001099248.1
• Gene: Rnf145 / 287212
• RGDID: 1309561
• Length: 664
• Species: Rattus norvegicus
• Alignment Length: 712
• Identity: 202/712 - (28%)
• Similarity: 351/712 - (49%)
• Gaps: 75/712 - (10%)

 Worm    45 KEMSIMVLETGLRLPGLLFIELLWRYQGFS-FEDISDDMMKQTPLSYFDIPTMLDFVHRRNFDHH 108
            ||....||...||:|.::.:::|:|:...| |:.|....:...||..:               .:
  Rat     4 KEKLEAVLNVALRVPSIMLLDVLYRWDVSSFFQQIQRSSLSNNPLFQY---------------KY 53

 Worm   109 AAIILSYFVIFISLMFLTLPLSRLIRMYSHFLSVFLFGVAYKLSAIYVDLEMKTG-EEELKLDGL 172
            .|:.:.|....:|::.||||...|:::|.:||:..|....:::|..||..|:::. |..:.|:.|
  Rat    54 LALNMHYVGYILSVVLLTLPRQHLVQLYLYFLTALLLYAGHQISRDYVRSELESAYEGPMYLEPL 118

 Worm   173 IKLERHGFHFLAQMLLVVLQSMLLEVDGEPWRVALPVFALPIVARMCGCPMDKLKNAHNYACTGT 237
             .:.|.....:.|:::..|.|.:::.. :.|  ......||::||:|..|::.:...:.:|
  Rat   119 -SMNRFTTALIGQLVVCTLCSCVMKTK-QIW--LFSAHMLPLLARLCLVPLETIVIINKFA---- 175

 Worm   238 MIFIATYMLYRAPSLI----KSTKTALRQIKAVFMVHG-LADGVAVLWRKLRILELLTFTWITMF 297
            |||....:||...|.:    ...|:|.|::..|..|:| ||.|:: ||.:|.:..|....|:.:|
  Rat   176 MIFTGLEVLYFLGSNLLVPYNLAKSAYRELVQVVEVYGLLALGMS-LWNQLVVPVLFMVFWLVLF 239

 Worm   298 LMVLYVELIDKGRTWSEVGRIL---LTGVAETTNTPITLAALAVSVSYVCKWIADLTKLITGGTR 359
            .:.:|.....:.:..|. .|:|   ||.:||..:||.:|..|..:||:|...:..|.|....|.|
  Rat   240 ALQIYSYFSTRDQPASR-ERLLFLFLTSIAECCSTPYSLLGLVFTVSFVALGVLTLCKFYLQGYR 303

 Worm   360 SHGHVLA-HSGYTEAVSVVILCIQTGFLGMQVEQKTILLALVLYIVISALLQSLFEIIEVVLLNL 423
            :..:..| :.|.||.|:::||.:|||.:.:||..:..||:::|:||::::|||:.||.:.::|.|
  Rat   304 AFMNDPAMNRGMTEGVTLLILAVQTGLIELQVVHRAFLLSIILFIVVASILQSMLEIADPIVLAL 368

 Worm   424 PSSPTASRARHARCICIALLLVVIPFFTTKTMLALLPIDIYTAIIIANSATVTARAIGVILKYIV 488
            .:|...|..:|.|.:.:.|.|:|.|.:....:.....:|.:..|||::|...:.:.:|.:..|::
  Rat   369 GASRDKSLWKHFRAVSLCLFLLVFPAYMAYMICQFFHMDFWLLIIISSSILTSLQVLGTLFIYVL 433

 Worm   489 LIVETKSEEPWEGIDDLTYYIDCANKGIELLAAKVVMVFGCMQVVKVGFSFATFAILLFHVIVNI 553
            .:||...:||.|.:||:.||::...:.:|.|.|..|:.:|..:.:...::.....|:..|...|:
  Rat   434 FMVEEFRKEPVENMDDVIYYVNGTYRLLEFLVALCVVAYGVSETIFGEWTVMGSMIIFIHSYYNV 498

 Worm   554 YKRLE-HTVSFIKNRNAAVKNINRLSKADVVQLREREDVCAICFIEMKEEARITPCKHYFHGPCL 617
            :.|.: ...||:..|: ||..|..|..|...||....|:||||:.:|| .|.||||.|:||..||
  Rat   499 WLRAQLGWKSFLLRRD-AVNKIKSLPIATKEQLERHNDICAICYQDMK-SAVITPCSHFFHAGCL 561

 Worm   618 RKWLAVKMVCPLCYTYMKEDDFDSKSSSSGTLNEVQQNEEGA----AVEENPENPE-EQPEAPNA 677
            :|||.|:..||||:.::|.   .|:....||....|....||    .::|.||.|: |.|..|.|
  Rat   562 KKWLYVQDTCPLCHCHLKN---SSQLPGLGTEPAPQPPVAGAEQNIVLQEGPEPPDHETPPGPGA 623

 Worm   678 ERAPGDMFDWDDLFGFRAERETRNRNEQRIHGARDMWPLLVDNDAYESDSDAGSEELVIEEE 739
            :...||..::       ..|.:.:|                     |.|:|.|....:.|.|
  Rat   624 QEGSGDNSEY-------INRSSASR---------------------EGDADPGDGPQIAEGE 657

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
rnf-145	NP_491382.2	TRC8_N	49..556	CDD:372682	139/517 (27%)
		RING-H2_RNF139_like	590..631	CDD:319390	24/40 (60%)
Rnf145	NP_001099248.1	TRC8_N	8..506	CDD:404574	140/522 (27%)
		HRD1	<520..643	CDD:227568	48/154 (31%)
		RING-H2_RNF145	533..575	CDD:319598	24/42 (57%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	199	1.000	Domainoid score	I1973
eggNOG	1	0.900	-	-		E1_COG5243
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	277	1.000	Inparanoid score	I1996
OMA	1	1.010	-	-		QHG46488
OrthoDB	1	1.010	-	-		D302551at33208
OrthoFinder	1	1.000	-	-		FOG0006288
OrthoInspector	1	1.000	-	-		oto26645
orthoMCL	1	0.900	-	-		OOG6_109881
Panther	1	1.100	-	-	O	PTHR22763
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X4575
SwiftOrtho	1	1.000	-	-
TreeFam	1	0.960	-	-
	13	12.840