DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Ascl1 and Fer1

DIOPT Version :9

Sequence 1:	NP_032579.2	Gene:	Ascl1 / 17172	MGIID:	96919	Length:	231	Species:	Mus musculus
Sequence 2:	NP_001262334.1	Gene:	Fer1 / 2768661	FlyBaseID:	FBgn0037475	Length:	256	Species:	Drosophila melanogaster

Alignment Length:	167	Identity:	42/167 - (25%)
Similarity:	68/167 - (40%)	Gaps:	40/167 - (23%)

- Green bases have known domain annotations that are detailed below.

Mouse    84 QRSSSPELMRCKRRLNFSGFGYSLPQQQPAAVARRNERERNRVKLVNLGFATLREHVPNGAANKK 148
            :||..|..::|..:         :.||:.||    |.|||.|::.:|..|..||.|:|.....|:
  Fly    70 RRSHKPRRLKCASQ---------MAQQRQAA----NLRERRRMQSINEAFEGLRTHIPTLPYEKR 121

Mouse   149 MSKVETLRSAVEYIRALQQLLDEHDAVSAAFQAGVLSPTISPNYSND------LNSMAGSPVSS- 206
            :|||:||:.|:.||..|.:::.:.   ....:.|:   ::..||..:      |....|....|
  Fly   122 LSKVDTLKLAISYITFLSEMVKKD---KNGNEPGL---SLQRNYQKEPPKKIILKDRTGGVAHSL 180

Mouse   207 --------------YSSDEGSYDPLSPEEQELLDFTN 229
                          |:......||..|..|.|..:.|
  Fly   181 SWYRKGDRYPGSKLYARTWTPEDPRGPHSQPLPLYNN 217

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Ascl1	NP_032579.2	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	1..24
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	39..92		3/7 (43%)
		HLH	129..171	CDD:197674	16/41 (39%)
Fer1	NP_001262334.1	HLH	92..144	CDD:197674	21/51 (41%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG4029
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810