DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Mas1 and CCHa1-R

DIOPT Version :9

Sequence 1:	NP_032578.2	Gene:	Mas1 / 17171	MGIID:	96918	Length:	324	Species:	Mus musculus
Sequence 2:	NP_611241.2	Gene:	CCHa1-R / 37004	FlyBaseID:	FBgn0050106	Length:	499	Species:	Drosophila melanogaster

Alignment Length:	315	Identity:	73/315 - (23%)
Similarity:	134/315 - (42%)	Gaps:	68/315 - (21%)

- Green bases have known domain annotations that are detailed below.

Mouse    31 IPIVHWVIMSISPLGFVENG-ILLWFLCFRMRRNPFTVYITHLSIADISLLF-CIFILSIDYALD 93
            :||:..:|..:..||   || :::.||..|..||....||..|::||:.::. .:.:.|..|.::
  Fly    84 VPILFALIFVVGVLG---NGTLIVVFLSVRQMRNVPNTYILSLALADLLVIITTVPLASTVYTVE 145

Mouse    94 YELSSGHHYTIVTLSVT-FLFGYNTG--LYLLTAISVERCLSVLYPI-WYRCH----RPKHQSAF 150
            |     ..|.....|:: |:...:.|  ::.|||:|.:|..:::.|: .:..|    |....:..
  Fly   146 Y-----WPYGSFLCSLSEFMKDVSIGVSVFTLTALSGDRYFAIVDPLRKFHAHGGGRRATRMTLA 205

Mouse   151 VCALLWALSCL---------------VTTMEYVMCIDSGEE---SHSRSDCRAVIIFIAILSFLV 197
            ....:|.|:.|               :.....|:|....||   ::::|        :.:|.|||
  Fly   206 TAVSIWLLAILCGLPALIGSNLKHLGINEKSIVICYPYPEEWGINYAKS--------MVLLHFLV 262

Mouse   198 FTPLMLVSSTILVVKIRKNTWASHS---------------SKLYIVIMVTIIIFLIFAMPMRVLY 247
            :..:.||...:..|.|..:...|.|               .|:.:.::..::||.|..:|..|.:
  Fly   263 YYAIPLVVIAVFYVLIALHLMYSASVPGEIQGAVRQVRARRKVAVTVLAFVVIFGICFLPYHVFF 327

Mouse   248 LLYYEYW-------SAFGN-LHNISLLFSTINSSANPFIYFFVGSSKKKRFRESL 294
            |.:| :|       :||.: |..::...|..||.|||...:||..:.:|.|...|
  Fly   328 LWFY-FWPTAQDDYNAFWHVLRIVAYCMSFANSCANPVALYFVSGAFRKHFNRYL 381

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Mas1	NP_032578.2	7tmA_MrgprH	32..306	CDD:320238	73/314 (23%)
		TM helix 1	33..59	CDD:320238	8/26 (31%)
		TM helix 2	65..88	CDD:320238	5/23 (22%)
		TM helix 3	106..134	CDD:320238	8/30 (27%)
		TM helix 4	146..166	CDD:320238	3/34 (9%)
		TM helix 5	191..216	CDD:320238	8/24 (33%)
		TM helix 6	220..250	CDD:320238	9/44 (20%)
		TM helix 7	258..283	CDD:320238	8/25 (32%)
CCHa1-R	NP_611241.2	7tm_4	88..>188	CDD:304433	28/107 (26%)
CCHa1-R	NP_611241.2	7tm_1	98..364	CDD:278431	63/282 (22%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	0	0.000