Protein Alignment Man2b2 and LManI

DIOPT Version :9

• Sequence 1: NP_032576.2
• Gene: Man2b2 / 17160
• MGIID: 1195262
• Length: 1018
• Species: Mus musculus
• Sequence 2: NP_001260350.1
• Gene: LManI / 34436
• FlyBaseID: FBgn0032253
• Length: 950
• Species: Drosophila melanogaster
• Alignment Length: 1057
• Identity: 287/1057 - (27%)
• Similarity: 449/1057 - (42%)
• Gaps: 182/1057 - (17%)

Mouse    27 IRAFVVPHSHMDVGWVFTVQE--------SMRAYAANVYTTVVAELVRGGQRRFIAVEQEFFRLW 83
            |...:|||||.||||:.||.:        ...|....:..|||.||::...||||.||..||..|
  Fly     2 INVHLVPHSHDDVGWLKTVDQYYYGSQNKIQHAGVQYILDTVVEELLKDSSRRFIQVETFFFAKW 66

Mouse    84 WDGVASEQQ---KQQVRQLLHEGRLEFVLGGQVMHDEAVTHLDDQILQLTEGHGFLYETFGI--R 143
            :    |||.   ::.|::|:.:|||||..|...|:|||..|....:.|...|..:|.:|||.  |
  Fly    67 Y----SEQTETVQRAVKKLVAQGRLEFAGGAWSMNDEATVHYQSVVDQFNLGLRYLKDTFGDCGR 127

Mouse   144 PQFSWHVDPFGASATTPTLFALAGFNAHLISRIDY-DLKDAMQEAQMLQFVWHGSPSLSGQQEIF 207
            |...|.:||||.|....::||...||....:|:|| |.|..|.:.:| :.:|..|.||. ...||
  Fly   128 PTVGWQIDPFGHSREMASIFAQMAFNGEFFARMDYVDKKQRMLDLEM-EMIWQSSESLK-NSNIF 190

Mouse   208 THVM-DHYSYCTPSHIPFSNRSGFYWNGVAVFPEPPPDG-VYPNMSEPVTGANIHLYAEALVANV 270
            |.:: :|||  .|        .||.:: :.....|..|| .|.|        |:.......:..|
  Fly   191 TGMLYNHYS--AP--------PGFCFD-INCEDAPIIDGESYDN--------NVDARVSEFIDYV 236

Mouse   271 KQRAAWFRTPHVLWPWGCDKQFFNASVQFDNMDPLLDYINQRTAQFG-ISVQYATLNDYFQALHA 334
            |..:..:|:.|::.|.|.|.|:.:|:|.|.|||.|:.|:|.|.:... ::|.|:|.:.|...||.
  Fly   237 KNMSKSYRSTHIMVPMGDDFQYEDAAVNFKNMDKLIKYVNDRQSTGSQVNVFYSTPSCYLYELHQ 301

Mouse   335 TNMTWGIRDHQDFLPYSSEPLQAWTGFYTSRSTLKGLARQASALLYAGESMFTRYMWPDPSGTLD 399
            ...||..:. :||.||||:....|||::|||.|.|...|.       |...|...........|.
  Fly   302 LKQTWPNKT-EDFFPYSSDSHSYWTGYFTSRPTQKRFHRD-------GNHFFQTVKQLSVLANLS 358

Mouse   400 PTWALQQLQQLRWAVSEVQHHDAITGTESPKVKNMYTEHLRMGMLGVRKLMVSIALGGPPGSGTG 464
            .|...:.|..|..|:..:|||||:||||...|.:.|...|...::|... ....||.......:|
  Fly   359 GTQYSEDLDNLSQAMGIMQHHDAVTGTEKQAVASDYDRLLFKAIVGAEN-SARDALRSLTNLTSG 422

Mouse   465 APKDIMGPQVTPVLSVDTRPVGYSASVYNPLAWKITTIITLTVAFPNVSVTDELGHPVSTQIQNS 529
            ..:..:...::..............::.||||...|..:.:.....|..||||.|..|.:::.
  Fly   423 EFESCLELNISVCAFTQDTANNVIVTLVNPLAHSSTQYVRVPAKNENYIVTDEKGREVFSEVV-- 485

Mouse   530 TKDPSAYDLLILTTIPGLNYRHYQVMHARGDQAGT---RELVAPRANTLKFSLKLRNQPSQEGKR 591
               |..:.:|.|...|. :.:|..|..|..|:...   |.|.:|: |..:..::...:.||:.
  Fly   486 ---PVPWQVLALEHRPN-DTQHELVFEASVDKIANFLIRVLPSPK-NIAEDQVQFPVERSQDE-- 543

Mouse   592 LVPVMNDCYILLFDQDTNMLHSIQDRQSNRTVRMTQEFLE-YQANWDVKQGPISDNYLFAPNNTA 655
             :.|......|.||..|..|.:::.......::.|....: |:.|....:...|..|:|.|....
  Fly   544 -LTVETSLVKLTFDTTTGGLKTVKMNGFTENIQQTFGIYKGYRGNNGESKNRSSGAYVFRPYGDI 607

Mouse   656 EPSWEAVGMEMVAGTLVTDIRQYFYRYITDQEYIYSIHTRLAHPSLAGELLCQRIEQQYRVGPL- 719
            |.....|.:....||.|.::.|:...:|:....||..              ..|:|.::.|||:
  Fly   608 EIVNNKVELSFYNGTKVKEVHQHVNEWISQVIRIYED--------------VNRVEFEWLVGPIP 658

Mouse   720 ---DLNREAILRTSSDLNSQQVLYSDNNGYQM------QRRPYKAFKSNPIPRNYYPMVQSAFIE 775
               |:.:|.|.|.||:::|:...|:|:||.::      ||..:....|..|..||||:.....::
  Fly   659 TDDDVGKEIITRFSSNISSKGKFYTDSNGREILERERNQREHFTPDMSEAISGNYYPVTGQISLQ 723

Mouse   776 DDKSRLVLLAERPHGVSSQGNGQVEVMLHRRLWNNLAWDLKYNLTLNDTSIVHPVLWLMLGPKST 840
            ||:.|:.||.:|..|.:|..:|::|:||||||.|:.|:.:  ...||:|
  Fly   724 DDEKRITLLNDRAQGGTSLKDGELELMLHRRLLNDDAFGV--GEALNET---------------- 770

Mouse   841 MTALHPRSGVAL-QHGPVVLLKELADEETPVHGPHNPWPVTLPPNLHL--QILSVPGWT-YSRSH 901
                  :.|..| ..|.:.|:.:..|.:               ||..|  ..|....|. :|:|:
  Fly   771 ------QYGTGLIARGKIYLILDAVDGK---------------PNQRLLQHQLDQHFWKFFSKSN 814

Mouse   902 --AQHLRNLQR---GHPEKPQANLQRVLLRLRHLYEAGEDPVLSRPATVDLKVVLRGLGSVVA-- 959
              |...||:..   |.||.         :.|..|....:|.:|.|....:.:      |:||:
  Fly   815 GVASVNRNMIPDFFGIPES---------VELLSLEPYSKDQILIRLENFNTE------GNVVSFN 864

Mouse   960 ------------VEERSLTGTWDVQMLQRWHWSTKTDHLKGHPTS------PPRP--------PG 998
                        :.|.:|.|...::.::|:.::  .|.....|:|      |..|        ..
  Fly   865 IYPLFESLDGYQIWETTLDGNMLLEDVKRFKFA--QDGTGSIPSSVEYYHAPHNPLTANSTMNAS 927

Mouse   999 GSIITVYPKEIRTFFIK 1015
            |.::|:.|.:||||.|:
  Fly   928 GFVVTLVPMQIRTFIIQ 944

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Man2b2	NP_032576.2	GH38N_AMII_Epman_like	27..352	CDD:212122	117/341 (34%)
		Alpha-mann_mid	358..439	CDD:214875	27/80 (34%)
		Glyco_hydro_38C	491..1012	CDD:285047	133/571 (23%)
LManI	NP_001260350.1	GH38N_AMII_LAM_like	2..276	CDD:212121	103/298 (35%)
		Alpha-mann_mid	323..398	CDD:286360	27/81 (33%)
		Glyco_hydro_38C	536..941	CDD:285047	109/477 (23%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1959
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11607
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.910